Autophagy, Infection, and the Immune Response - Couverture rigide

Couverture rigide

ISBN 10 : 1118677641 ISBN 13 : 9781118677643

Editeur : Wiley-Blackwell, 2015

Synopsis

The relationship between infection and immunity and autophagy, a pathway of cellular homeostasis and stress response, has been a rapidly growing field of study over the last decade. While some cellular processes are pro- or anti-infection, autophagy has been proven to be both: a part of the innate immune response against some microbes, and a cellular pathway subverted by some pathogens to promote their own replication.

Autophagy, Infection, and the Immune Response provides a unified overview of the roles of cellular autophagy during microbial infection. Introductory chapters ground the reader by delineating the autophagic pathway from a cellular perspective, and by listing assays available for measuring autophagy. Subsequent chapters address virus interactions with autophagy machinery, the various roles of autophagy parasitic infection, and interactions of bacteria with the autophagic pathway. Concluding chapters explore the relationships of autophagy to systemic immune responses, including antigen presentation, ER stress, and production of IFN-gamma.

Designed as a resource for those interested in initiating studies on the relationship between autophagy and infection or immunity, Autophagy, Infection, and the Immune Response combines practical state-of the art technique descriptions with an overview of the wide variety of known interactions between pathogens and the autophagic pathway.

A propos du livre

À propos de l?auteur

William T. Jackson is Assistant Professor of Microbiology at the Medical College of Wisconsin in Milwaukee, Wisconsin, USA

Michele S. Swanson is Professor of Microbiology and Immunology at the University of Michigan Medical School, Ann Arbor, Michigan, USA

Détails de l'édition

• Éditeur: Wiley-Blackwell
• Date d'édition: 2015
• Langue: anglais
• ISBN 10: 1118677641
• ISBN 13: 9781118677643
• Reliure: Relié
• Nombre de pages: 352
• Éditeur: Jackson William T., Swanson Michele S.
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible