Translational ADMET for Drug Therapy: Principles, Methods, and Pharmaceutical Applications - Couverture rigide

Yanni, Souzan B.

 
9781118838273: Translational ADMET for Drug Therapy: Principles, Methods, and Pharmaceutical Applications
Couverture rigide
ISBN 10 : 1118838270 ISBN 13 : 9781118838273
Editeur : Wiley-Interscience, 2015

Synopsis

Serving as a practical handbook about ADMET for drug therapy, this book presents effective technologies, methods, applications, data interpretation, and decision-making tactics for pharmaceutical and preclinical scientists. Chapters cover case studies and in vivo, in vitro, and computational tools for drug discovery and development, with new translational approaches to clinical drug investigations in various human populations.

  • Illustrates ADME properties, from bedside to bench and bench to bedside, for the design of safe and effective medicine in human populations
  • Provides examples that demonstrate the integration of in vitro, in vivo, and in silico data to address human PKPD and TKTD and help determine the proper therapeutic dosage
  • Presents successful tools for evaluating drugs and covers current translational ADMET with regulatory guidelines
  • Offers a hands-on manual for researchers and scientists to design and execute in vitro, in silico, preclinical, and clinical studies
  • Includes discussion of IND / NDA filing and drug labeling to support drug registration and approval

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

À propos de l'auteur

Souzan B. Yanni, PhD, is Founder and President of DMPK Consultants, Inc., which leads ADME/PK in support of preclinical and clinical investigations for of pharmaceutical and biotech companies. She has over 20 years of hands-on leadership experience in planning, executing, and overseeing drug discovery and early development for therapeutic programs with national and international pharmaceutical companies, biotech groups, and CROs. Dr. Yanni possesses a PhD in Pharmaceutical Sciences, MS in Biochemistry, and BS in Chemistry. She is the author of several peer-reviewed articles, review articles, and book chapters on ADMET/PK as well as an external reviewer / editor for other journals.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Wiley-Interscience
Date d'édition
2015
Langue
anglais
ISBN 10 
1118838270
ISBN 13 
9781118838273
Reliure
Relié
Numéro d'édition
1
Nombre de pages
352
Coordonnées du fabricant
non disponible
Personne responsable
non disponible