Articles liés à Oral Formulation Roadmap from Early Drug Discovery...
Synopsis
Detailing formulation approaches by stage of discovery to early development, this book gives a "playbook" of practical and efficient strategies to formulate drug candidates with the least chance of failing in clinical development.
- Comes from contributing authors with experience developing formulations on the frontlines of the pharmaceutical industry
- Focuses on pre (or non-) clinical and early stage development, the phases where most compounds are used in drug research
- Features case studies to illustrate practical challenges and solutions in formulation selection
- Covers regulatory filing, drug metabolism and physical and chemical properties, toxicology formulation, biopharmaceutics classification system (BCS), screening approaches, early stage clinical formulation development, and outsourcing
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
À propos de l?auteur
Elizabeth Kwong, PhD, retired from Merck & Co., Inc. in 2011, after 23 years of service. She then established her own company, Kwong Eureka Solutions, as a consultant for small start-up companies and specialty drug products. Dr. Kwong is on the Board of Directors for the Canadian Society of Pharmaceutical Scientists and is also an adjunct professor in the Department of Pharmaceutics at the University of Montreal and Department of Chemistry at Concordia University. More recently, Dr. Kwong also co-founded a start-up company, Giiant Pharma, working on delivering a colon specific PDEIV Inhibitor prodrug for the treatment of ulcerative colitis.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Oral Formulation Roadmap from Early Drug Discovery to Development
Edité par
Wiley, 2017
ISBN 10 : 1118907337
ISBN 13 : 9781118907337
Ancien ou d'occasion
Couverture rigide
Vendeur : Goodwill of Silicon Valley, SAN JOSE, CA, Etats-Unis
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Etat : acceptable. Supports Goodwill of Silicon Valley job training programs. The cover and pages are in Acceptable condition! Any other included accessories are also in Acceptable condition showing use. Use can include some highlighting and writing, page and cover creases as well as other types visible wear such as cover tears discoloration, staining, marks, scuffs, etc. All pages intact. N° de réf. du vendeur GWSVV.1118907337.A
Quantité disponible : 1 disponible(s)
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Oral Formulation Roadmap from Early Drug Discovery to Development
Edité par
Wiley, 2017
ISBN 10 : 1118907337
ISBN 13 : 9781118907337
Ancien ou d'occasion
Couverture rigide
Edition originale
Vendeur : killarneybooks, Inagh, CLARE, Irlande
Évaluation du vendeur 5 sur 5 étoiles
Hardcover. Etat : Very Good. 1st Edition. Hardcover, x + 252 pages, NOT ex-library. Book is clean and bright throughout with unmarked text, free of inscriptions and stamps, firmly bound. A tiny crease to the tip of upper corner of several leaves. Issued without a dust jacket. -- Contents: 1 Introduction / Elizabeth Kwong; 2 Lead Identification/Optimization / Mei Wong & Mark McAllister; 3 Oral Drug Formulation Development in Pharmaceutical Lead Selection Stage / Shayne Cox Gad; 4 Bridging End of Discovery to Regulatory Filing: Formulations for IND? and Registration?Enabling Nonclinical Studies / Evan A. Thackaberry; 5 Planning the First Clinical Trials with Clinical Manufacturing Organization (CMO) / Elizabeth Kwong & Caroline McGregor; 6 Formulation Strategies for High Dose Toxicology Studies: Case Studies / Dennis H. Leung; 7 Formulation, Analytical, and Regulatory Strategies for First?in?Human Clinical Trials / Lorenzo Capretto; Index -- Many of the challenges facing drug discovery and development stem from a failure to properly identify formulations that translate from preclinical to clinical phases. Further, a lack of collaboration and proper integration between formulation and discovery scientists contribute significantly to most failures in the clinic. Lastly, the regulatory requirements for formulations also increase the timelines and costs of bringing a drug candidate forward. Written to address these many challenges and issues, this book describes and explains the key factors that help determine the types of formulation needed throughout the stages of drug discovery. Detailing formulation approaches by stage of discovery to early development, Oral Formulation Roadmap from Early Drug Discovery to Development gives a 'playbook' of practical and efficient strategies to formulate drug candidates with the least chance of failing in clinical development. A key reference for practicing pharmaceutical scientists, this book provides a valuable resource that: - Comes from contributing authors with experience developing formulations on the frontlines of the pharmaceutical industry; - Focuses on pre (or non-) clinical and early stage development, the phases where most compounds are used in drug research; - Features case studies to illustrate practical challenges and solutions; - Covers regulatory filing, drug metabolism and properties, biopharmaceutics classification system (BCS), screening approaches, toxicology studies, clinical formulation development, and outsourcing. N° de réf. du vendeur 007161
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ORAL FORMULATION ROADMAP FROM EARLY DRUG DISCOVERY TO DEVELOPMENT (HB 2017)
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Oral Formulation Roadmap from Early Drug Discovery to Development
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Oral Formulation Roadmap from Early Drug Discovery to Development
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Oral Formulation Roadmap from Early Drug Discovery to Development
Edité par
John Wiley & Sons, 2017
ISBN 10 : 1118907337
ISBN 13 : 9781118907337
Neuf
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Vendeur : Books Puddle, New York, NY, Etats-Unis
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Etat : New. pp. 320. N° de réf. du vendeur 26374753863
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Oral Formulation Roadmap from Early Drug Discovery to Development
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Oral Formulation Roadmap from Early Drug Discovery to Development Format: Hardcover
Edité par
John Wiley and Sons, 2017
ISBN 10 : 1118907337
ISBN 13 : 9781118907337
Neuf
Couverture rigide
Vendeur : INDOO, Avenel, NJ, Etats-Unis
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Oral Formulation Roadmap from Early Drug Discovery to Development
Edité par
John Wiley & Sons, 2017
ISBN 10 : 1118907337
ISBN 13 : 9781118907337
Neuf
Couverture rigide
Vendeur : Majestic Books, Hounslow, Royaume-Uni
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Etat : New. pp. 320. N° de réf. du vendeur 371324312
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Oral Formulation Roadmap from Early Drug Discovery to Development
Edité par
John Wiley & Sons, 2017
ISBN 10 : 1118907337
ISBN 13 : 9781118907337
Neuf
Couverture rigide
Vendeur : Biblios, Frankfurt am main, HESSE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Etat : New. pp. 320. N° de réf. du vendeur 18374753869
Quantité disponible : 4 disponible(s)