Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants - Couverture rigide

Couverture rigide

ISBN 10 : 1119329701 ISBN 13 : 9781119329701

Editeur : John Wiley & Sons Inc, 2018

Synopsis

Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.

- Covers both basic science and applied technology / methods
- Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects
- Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development
- Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria

A propos du livre

À propos de l'auteur

Yvonne Will, PhD, is a Senior Director and the Head of Science and Technology Strategy, Drug Safety Research and Development at Pfizer, Connecticut, USA. In addition to the prior edition of this book, she co-edited Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers(Wiley, 2016).

James A. Dykens, PhD, oversees EyeCyte Therapeutics, a start-up developing treatments for progressive blinding diseases via targeting mitochondrial dysfunction. He co-edited the first edition of this book.

Détails de l'édition

• Éditeur: John Wiley & Sons Inc
• Date d'édition: 2018
• Langue: anglais
• ISBN 10: 1119329701
• ISBN 13: 9781119329701
• Reliure: Relié
• Nombre de pages: 816
• Éditeur: Will Yvonne, Dykens James A.
• Coordonnées du fabricant: JOSSEY-BASS; https://www.wiley.com/en-us; ; 111 River Street; Hoboken; NJ; 7030; Etats-Unis
• Personne responsable: non disponible