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Synopsis
Covering even more adaptive designs, this second edition offers a detailed framework to understand the use of various adaptive design methods in clinical trials. It includes 12 new chapters, more analytical methods, 20 new SAS macros and R functions, and enhanced end-of-chapter problems that give readers hands-on practice addressing issues encountered in designing real-life adaptive trials. The book compares various methods using SAS and R simulations and explains how to analyze data in adaptive trials.
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Chang, Mark
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Chang, M: Adaptive Design Theory and Implementation Using SA
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Kartoniert / Broschiert. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Chang, MarkGet Up to Speed on Many Types of Adaptive DesignsSince the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new dev. N° de réf. du vendeur 595369006
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Adaptive Design Theory and Implementation Using SAS and R
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Taylor & Francis Ltd (Sales) Okt 2016, 2016
ISBN 10 : 1138034231
ISBN 13 : 9781138034235
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Get Up to Speed on Many Types of Adaptive DesignsSince the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second Edition offers a detailed framework to understand the use of various adaptive design methods in clinical trials. New to the Second EditionTwelve new chapters covering blinded and semi-blinded sample size reestimation design, pick-the-winners design, biomarker-informed adaptive design, Bayesian designs, adaptive multiregional trial design, SAS and R for group sequential design, and much moreMore analytical methods for K-stage adaptive designs, multiple-endpoint adaptive design, survival modeling, and adaptive treatment switchingNew material on sequential parallel designs with rerandomization and the skeleton approach in adaptive dose-escalation trialsTwenty new SAS macros and R functionsEnhanced end-of-chapter problems that give readers hands-on practice addressing issues encountered in designing real-life adaptive trialsCovering even more adaptive designs, this book provides biostatisticians, clinical scientists, and regulatory reviewers with up-to-date details on this innovative area in pharmaceutical research and development. Practitioners will be able to improve the efficiency of their trial design, thereby reducing the time and cost of drug development. 706 pp. Englisch. N° de réf. du vendeur 9781138034235
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Adaptive Design Theory and Implementation Using SAS and R
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Adaptive Design Theory and Implementation Using SAS and R, Second Edition (Chapman & Hall/CRC Biostatistics Series)
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Adaptive Design Theory and Implementation Using SAS and R (Chapman & Hall/CRC Biostatistics Series)
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Adaptive Design Theory and Implementation Using SAS and R (Chapman & Hall/CRC Biostatistics Series)
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ISBN 13 : 9781138034235
Neuf
Couverture souple
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Adaptive Design Theory and Implementation Using SAS and R, Second Edition (Chapman & Hall/CRC Biostatistics Series)
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Paperback. Etat : Brand New. 2nd revised edition. 706 pages. 9.25x6.14x1.73 inches. In Stock. This item is printed on demand. N° de réf. du vendeur __1138034231
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Adaptive Design Theory and Implementation Using SAS and R
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Get Up to Speed on Many Types of Adaptive DesignsSince the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second Edition offers a detailed framework to understand the use of various adaptive design methods in clinical trials. New to the Second EditionTwelve new chapters covering blinded and semi-blinded sample size reestimation design, pick-the-winners design, biomarker-informed adaptive design, Bayesian designs, adaptive multiregional trial design, SAS and R for group sequential design, and much moreMore analytical methods for K-stage adaptive designs, multiple-endpoint adaptive design, survival modeling, and adaptive treatment switchingNew material on sequential parallel designs with rerandomization and the skeleton approach in adaptive dose-escalation trialsTwenty new SAS macros and R functionsEnhanced end-of-chapter problems that give readers hands-on practice addressing issues encountered in designing real-life adaptive trialsCovering even more adaptive designs, this book provides biostatisticians, clinical scientists, and regulatory reviewers with up-to-date details on this innovative area in pharmaceutical research and development. Practitioners will be able to improve the efficiency of their trial design, thereby reducing the time and cost of drug development. N° de réf. du vendeur 9781138034235
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Adaptive Design Theory and Implementation Using SAS and R, Second Edition (Chapman & Hall/CRC Biostatistics Series)
Edité par
Chapman and Hall/CRC, 2016
ISBN 10 : 1138034231
ISBN 13 : 9781138034235
Neuf
Couverture souple
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