Methods for Studying Nucleic Acid/Drug Interactions - Couverture souple

Couverture souple

ISBN 10 : 1138382035 ISBN 13 : 9781138382039

Editeur : CRC Press, 2018

Synopsis

This book describes emerging, non-conventional methods for probing the interactions of small molecules with nucleic acids as well as modern computational methods for assessment. By highlighting novel methods for nucleic acid/ligand interactions, the text presents drug developing companies with a survey of possible future techniques as well as their drawbacks and advantages with respect to common techniques. In addition, and perhaps more importantly, this book is designed to inspire young scientists to continue and advance these methods into fruition, especially in light of current capabilities for assay miniaturization and enhanced sensitivity using microfluidics and nanomaterials.

A propos du livre

À propos de l?auteur

Meni Wanunu completed his Ph.D. in 2005 at the Weizmann Institute of Science, where he specialized in supramolecular chemistry, self-assembly, and nanomaterials science. He then carried out a postdoctoral position at Boston University and a research associate position at the University of Pennsylvania, where he developed ultrasensitive synthetic nanopores for nucleic acid analysis at the single-molecule level. Currently, he is an Assistant Professor at the Department of Physics and the Department of Chemistry and Chemical Biology at Northeastern University, Boston. His research interests include developing chemical approaches for investigating biomolecular structure and behavior, nucleic acid mechanics and dynamics, and probing biological processes at the single-molecule level.

Yitzhak Tor carried out his doctorate work at the Weizmann Institute of Science, earning his Ph.D. in 1990. After a postdoctoral stay at the California Institute of Technology (1990-1993), he took his first faculty position at the University of Chicago. In 1994, he moved to the University of California, San Diego, where he is currently a Professor of Chemistry and Biochemistry and the Traylor Scholar in Organic Chemistry. His research interests are diverse and include chemistry and biology of nucleic acids, the discovery of novel antiviral and antibacterial agents, as well as the development of cellular delivery agents and fluorescent probes. He is currently the Editor in Chief of Perspectives in Medicinal Chemistry (http: //la-press.com/journal.php?journal_id=25) and Organic Chemistry Insights (http: //www.la-press.com/organic-chemistry-insights-journal-j104). Away from chemistry, his interests are predominantly in music, playing, recording and producing his own instrumental CDs.

Détails de l'édition

• Éditeur: CRC Press
• Date d'édition: 2018
• Langue: anglais
• ISBN 10: 1138382035
• ISBN 13: 9781138382039
• Reliure: Broché
• Nombre de pages: 408
• Éditeur: Wanunu Meni, Tor Yitzhak
• Coordonnées du fabricant: non disponible
• Personne responsable: gpsr@libri.de; gpsr@libri.de; ; Friedensallee 273; Hamburg; 22763; Allemagne