It is common to study the electric activity of neurons by measuring the electric potential in the extracellular space of the brain. However, interpreting such measurements requires knowledge of the biophysics underlying the electric signals. Written by leading experts in the field, this volume presents the biophysical foundations of the signals as well as results from long-term research into biophysics-based forward-modeling of extracellular brain signals. This includes applications using the open-source simulation tool LFPy, developed and provided by the authors. Starting with the physical theory of electricity in the brain, this book explains how this theory is used to simulate neuronal activity and the resulting extracellular potentials. Example applications of the theory to model representations of real neural systems are included throughout, making this an invaluable resource for students and scientists who wish to understand the brain through analysis of electric brain signals, using biophysics-based modeling.
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Geir Halnes is a Research Scientist with a background in physics and theoretical biology. For the last one-and a half decade, he has worked in the Computational Neuroscience Lab at the Norwegian University of Life Sciences. His research focuses on the fundamental physical processes in neurons, glial cells and brain tissue.
Torbjørn V. Ness is a Research Scientist with a background in computational neuroscience, who has more than a decade of experience in modeling extracellular potentials, including Finite Element simulations of neural tissue and measurement equipment. Torbjørn is one of the developers of LFPy, a software for calculating brain signals from simulated neural activity.
Solveig Næss is a Senior Researcher with a background in physics. She got her Ph.D. in computational neuroscience through an international Ph.D. program at the University of Oslo, Simula Research Laboratory, and the University of California, San Diego. Solveig specializes in biophysical modeling of electric brain signals.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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