Articles liés à Characterizing Biotherapeutics: Analytical Methods...

Characterizing Biotherapeutics: Analytical Methods for Diverse Modalities - Couverture rigide

 
9781394236114: Characterizing Biotherapeutics: Analytical Methods for Diverse Modalities

Synopsis

"Although monoclonal antibodies comprise the largest share of approved therapeutic molecules, many new non-antibody modalities are being evaluated in the clinic. These new biologics are more complex, which comes as a result of a greater understanding of underlying disease biology as well as advanced engineering approaches. All recombinant proteins made for both research purposes and as therapeutic moieties undergo in depth analytical characterization using a variety of tools including mass spectrometry. As molecules increase in their complexity, the analytical field has had to keep up with improvements in the high-throughput, complexity, and sensitivity of characterization techniques"-- Provided by publisher.

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À propos de l'auteur

Jennie R. Lill, PhD, is the Executive Director of the Proteomic and Genomic Technologies Department at Genentech, where she has worked since 2004. With over 90 peer-reviewed publications and three books, including Analytical Characterization of Biotherapeutics, her work focuses on cutting-edge analytical techniques in drug discovery and development.

Wendy Sandoval was the Director of Translational Mass Spectrometry in Research at Genentech, where she had been a pivotal contributor for over 30 years. She has authored more than 100 scientific publications and co-authored two books, including Analytical Characterization of Biotherapeutics. She now runs a plant nursery and botanical garden in Northern California (https: //botanicanurseryandgardens.com/) and enjoys playing in dirt.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.