Solid-state Materials in Pharmaceutical Chemistry: Properties, Characterization and Applications - Couverture rigide

Name: Solid-state Materials in Pharmaceutical Chemistry: Properties, Characterization and Applications
Author: Byrn, Stephen R.; Zografi, George; Chen, Xiaoming (Sean)
ISBN: 9781394254446

Byrn, Stephen R.; Zografi, George ; Chen, Xiaoming (Sean)

9781394254446: Solid-state Materials in Pharmaceutical Chemistry: Properties, Characterization and Applications

Couverture rigide

ISBN 10 : 139425444X ISBN 13 : 9781394254446

Editeur : John Wiley & Sons Inc, 2025

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"Solid-state chemistry and the solid-state properties of pharmaceutical materials play an ever-increasing and important role in pharmaceutical development. There is much more emphasis on physical characterization since the ICH Q6A guidance on specifications was released"-- Provided by publisher.

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� propos de l'auteur

Stephen R. Byrn, PhD, Charles B. Jordan Professor of Medicinal Chemistry in the Department of Industrial and Molecular Pharmaceutics, Purdue University.

George Zografi, PhD, Edward Kremers Professor Emeritus of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison.

Xiaoming (Sean) Chen, PhD, works in the field of pharmaceutical product development and held various positions at Schering-Plough, OSI Pharmaceuticals, Astellas Pharma, Shionogi Inc, Antares Pharma, Arvinas, and Improved Pharma.

Les informations fournies dans la section � A propos du livre � peuvent faire r�f�rence � une autre �dition de ce titre.

�diteur: John Wiley & Sons Inc
Date d'�dition: 2025
Langue: anglais
ISBN 10: 139425444X
ISBN 13: 9781394254446
Reliure: Reli�
Num�ro d'�dition: 2
Nombre de pages: 560
Coordonn�es du fabricant: Easy Access System Europe O�, 16879218
gpsr.requests@easproject.com

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Solid-State Materials in Pharmaceutical Chemistry: Properties, Characterization, and Applications

Byrn, Stephen R.,Zografi, George,Chen, Xiaoming (Sean)

Edit� par Wiley, 2025

ISBN 10 : 139425444X ISBN 13 : 9781394254446

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Solid-State Materials in Pharmaceutical Chemistry: Properties, Characterization, and Applications

Byrn, Stephen R.,Chen, Xiaoming (Sean),Zografi, George

Edit� par Wiley, 2025

ISBN 10 : 139425444X ISBN 13 : 9781394254446

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Solid-State Materials in Pharmaceutical Chemistry

Stephen R. Byrn

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Solid-state Materials in Pharmaceutical Chemistry : Properties, Characterization and Applications

Byrn, Stephen R.; Zografi, George; Chen, Xiaoming

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ISBN 10 : 139425444X ISBN 13 : 9781394254446

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Solid-State Materials in Pharmaceutical Chemistry (Hardcover)

Stephen R. Byrn

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ISBN 10 : 139425444X ISBN 13 : 9781394254446

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Hardcover. Etat : new. Hardcover. Updated and expanded information on the properties of pharmaceutical solids and their impact on drug product performance, quality, and stability Solid-State Materials in Pharmaceutical Chemistry provides readers with a comprehensive and up-to-date resource for understanding and controlling the solid-state properties of pharmaceutical materials, enabling the development of safe and effective medicines including small molecule compounds, peptides, proteins, and nucleotides. This new edition covers the significant transformations in the landscape of pharmaceutical research, development, and manufacturing since the previous edition was published, presenting both novel challenges and unprecedented opportunities. New chapters in this edition cover physical and chemical properties of RNA therapeutics, a frontier to many life-saving medicines and vaccines including Covid vaccines, and final stage drug substance manufacturing and control, addressing challenges in API process development including impurity purging, chiral separation, final form preparation, particle size reduction, and nitrosamine control. Readers will also find other updated topics including bulk and surface properties of solids, lipid nanoparticles, applications of pharmaceutical solvates in impurity purging and final form preparation, pharmaceutical cocrystal engineering to enable chiral separation, the emerging technique of microcrystal electron diffraction in solid form characterization, poor wettability of APIs, oral delivery of peptides such as semaglutide, injectable drug-device combination products, and N-nitrosamine control in drug product. This updated and revised Second Edition still features: Physical and chemical properties of solid-state pharmaceuticals such as amorphous forms, mesophases, polymorphs, hydrates/solvates, salts, co-crystals, nano-particles, and solid dispersionsCharacterization techniques for solid form identification and physical attribute analysis such as X-Ray powder diffraction, thermal analysis, microscopy, spectroscopy, solid state NMR, particle analysis, water sorption, mechanical property testing, solubility, and dissolutionApplications of pharmaceutical chemistry and physical characterization techniques in developing and testing drug substances and drug products for small molecules and biopharmaceuticals This book is an essential resource on the subject for formulation scientists, process chemists, medicinal chemists, and analytical chemists. The book will also appeal to quality control, quality assurance, and regulatory affair specialists and advanced undergraduate and graduate students in pharmaceutical chemistry, drug delivery, material science, crystal engineering, pharmaceutics, and biopharmaceutics. "Solid-state chemistry and the solid-state properties of pharmaceutical materials play an ever-increasing and important role in pharmaceutical development. There is much more emphasis on physical characterization since the ICH Q6A guidance on specifications was released"-- Provided by publisher. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. N� de r�f. du vendeur 9781394254446

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Solid-state Materials in Pharmaceutical Chemistry : Properties, Characterization and Applications

Byrn, Stephen R.; Zografi, George; Chen, Xiaoming

Edit� par Wiley, 2025

ISBN 10 : 139425444X ISBN 13 : 9781394254446

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Solid-State Materials in Pharmaceutical Chemistry: Properties, Characterization, and Applications

Byrn, Stephen R Stephen R Byrn, George Zografi,Chen,

Edit� par Wiley -, 2025

ISBN 10 : 139425444X ISBN 13 : 9781394254446

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hardcover. Etat : New. Brand new book, sourced directly from publisher. Dispatch time is 24-48 hours from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely. N� de r�f. du vendeur 6666-GRD-9781394254446

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