Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems. 192 pp. Englisch. N� de r�f. du vendeur 9781402063145

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Evolving Methods for Macromolecular Crystallography

Read, Randy J.|Sussman, Joel L.

Edit� par Springer Netherlands, 2007

ISBN 10 : 1402063148 ISBN 13 : 9781402063145

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Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proceedings of the NATO Advanced Study Institute on Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of CBRN agents, Erice, Italy, 19-28 May 2005|Arises from the renowned Erice Schoo. N� de r�f. du vendeur 4094474

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Evolving Methods for Macromolecular Crystallography : The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents

Randy J Read

Edit� par Springer Nature Singapore, 2007

ISBN 10 : 1402063148 ISBN 13 : 9781402063145

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Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne

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Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume comprises papers presented at the 2005 edition of the 'Crystallography of Molecular Biology' courses that have been held since 1976 at the Ettore Majorana Centre for Scientific Culture in Erice, Italy. This series of courses is renowned for bringing leaders in the field of macromo- cular crystallography together with highly motivated students, in a beautiful and intimate location that encourages people to interact. The warm and informal atmosphere at these Erice conferences, especially these on cryst- lography, has helped to foster long-term scientific interactions and new int- national friendships that have often lasted for the lifetime of the scientists. The course was financed by NATO as an Advanced Study Institute and by the European Commission as a EuroSummerSchool. The papers span the breadth of material presented in the course, which emphasized the practical aspects of modern macromolecular crystallography and its applications. One must start with crystals: Bergfors showed how to improve initial crystals through seeding, while Byrne discussed the difficult problem of crystallizing membrane proteins. The collection of optimal diffraction data requires both careful preparation of cryo-cooled crystals (Garman) and proper processing of the diffraction images (Leslie). To obtain images of electron density, one needs estimates of the phases of the diffracted spots. Sheldrick presented the background to the sing- wavelength anomalous diffraction (SAD) method, which has been gaining popularity, and McCoy discussed the basis of modern maximum likelihood methods for treating information in experimental phasing. N� de r�f. du vendeur 9781402063145

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