Statistical Methods for QTL Mapping - Couverture rigide

Chen, Zehua

Couverture rigide

ISBN 10 : 1439868301 ISBN 13 : 9781439868300

Editeur : Chapman & Hall/CRC, 2013

Synopsis

While numerous advanced statistical approaches have recently been developed for quantitative trait loci (QTL) mapping, the methods are scattered throughout the literature. Statistical Methods for QTL Mapping brings together many recent statistical techniques that address the data complexity of QTL mapping.

After introducing basic genetics topics and statistical principles, the author discusses the principles of quantitative genetics, general statistical issues of QTL mapping, commonly used one-dimensional QTL mapping approaches, and multiple interval mapping methods. He then explains how to use a feature selection approach to tackle a QTL mapping problem with dense markers. The book also provides comprehensive coverage of Bayesian models and MCMC algorithms and describes methods for multi-trait QTL mapping and eQTL mapping, including meta-trait methods and multivariate sequential procedures.

This book emphasizes the modern statistical methodology for QTL mapping as well as the statistical issues that arise during this process. It gives the necessary biological background for statisticians without training in genetics and, likewise, covers statistical thinking and principles for geneticists. Written primarily for geneticists and statisticians specializing in QTL mapping, the book can also be used as a supplement in graduate courses or for self-study by PhD students working on QTL mapping projects.

A propos du livre

À propos de l?auteur

Zehua Chen

Détails de l'édition

• Éditeur: Chapman & Hall/CRC
• Date d'édition: 2013
• Langue: anglais
• ISBN 10: 1439868301
• ISBN 13: 9781439868300
• Reliure: Relié
• Nombre de pages: 308
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible