Targeted Cancer Immune Therapy - Couverture rigide

Couverture rigide

ISBN 10 : 1441901698 ISBN 13 : 9781441901699

Editeur : Springer-Verlag New York Inc., 2009

Synopsis

Stimulation of the immune system's ability to control and destroy tumors cont- ues to be the goal of cancer immune therapy; but the scope has rapidly expanded; approaches are constantly updated; new molecules are continually introduced; and immune mechanisms are becoming better understood. This book has no intention of covering every aspect of immune therapy but rather focuses on the novelty of cancer immune therapy in an attempt to give readers an opportunity to absorb the new aspects of immune therapy from a single source. In this regard, three areas were selected: cytokine immune therapy, cell-based immune therapy, and targeted immune therapy. In each of these three sections, only the novel aspects of immune therapy were described instead of attempting to cover any historical achievement. In the first section, Cytokine Immune Therapy, the IL12 family, IL18, IL21, IL24, IL28, and IL29 were emphasized in regard to the an- tumor function and application in treating tumors. Most of these selected cyt- ines were discovered in last 10 years. In the second section, Cell-based Immune Therapy, the focus was engineering potent immune regulatory or effector cells such as dendritic cells, T cells, and stem cells. Cell engineering design is primarily based on the increased understanding of the interaction of tumor antigen-presenting cells, antigen- specific effector cells, and the tumor microenvironment.

A propos du livre

Présentation de l'éditeur

This comprehensive book covers novel immune therapeutic approaches, including cytokine therapy, engineered cell therapy, and the application of tumor-targeted antibodies for generating tumor-specific cell therapy, TLR ligand therapy and cytokine therapy.

Détails de l'édition

• Éditeur: Springer-Verlag New York Inc.
• Date d'édition: 2009
• Langue: anglais
• ISBN 10: 1441901698
• ISBN 13: 9781441901699
• Reliure: Relié
• Nombre de pages: 354
• Éditeur: Lustgarten Joseph, Cui Yan, Li Shulin
• Coordonnées du fabricant: Springer-Verlag GmbH; customerservice@springernature.com; ; Tiergartenstraße 17; Heidelberg; Baden-Württemberg; 69121; Allemagne