Articles liés à Targeted Drug Strategies for Cancer and Inflammation

Targeted Drug Strategies for Cancer and Inflammation - Couverture souple

 
9781441984180: Targeted Drug Strategies for Cancer and Inflammation

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Synopsis

Biological Role, Properties and Therapeutic Applications of the Reduced Folate Carrier (RFC-SLC19A1) and the Proton-Coupled Folate Transporter (PCFT-SLC46A1).- Folate Receptors and Therapeutic Applications.- Hormonal Control of Folate Receptor Genes.- Folate Receptor Targeted Radionuclide Imaging Agents.- Folate receptor targeted thymidylate synthase inhibitors.- Discovery of novel antifolate inhibitors of de novo purine nucleotide biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry.- Folate-receptor targeted cancer chemotherapy.- Anti-FR antibody generation and engineering: development of new therapeutic tools.- Folate Receptor Positive Macrophages: Cellular Targets for Imaging and Therapy of Inflammatory and Autoimmune Diseases.- Targeting Activated Macrophages via a Functional Folate Receptor for Potential Treatment of Autoimmune/Inflammatory Disorders.-

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