Introduction.- Development of the concept of wake- and sleep -promoting systems in the brainstem and hypothalamus.- Dynamic NREM sleep regulation models.- Recognition of spontaneous and evoked arousal- and sleep-like (antiarousal) phasic events.- The cyclic structure of sleep - Relationship between the macro-structural slopes of cycles and micro-structural dynamics.- Changing views of NREM sleep homeostatic regulation.- Homeostatic features of CAP system and the physiological mechanism of reactive slow wave activity.- Slow wave activity as substrate of homeostatic regulation.- Need of slow wave activity and cognitive functions.- Overview.
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