This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
Dr. Florian Frommlet is a researcher in the Center for Medical Statistics, Informatics, and Intelligent Systems at the Medical University of Vienna, Austria.
Dr. Malgorzata Bogdan is an Associate Professor in the Institute of Mathematics at Wroclaw University, Poland.
Dr. David Ramsey is a Senior Lecturer in the Department of Operations Research at Wroclaw University of Technology, Poland.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Thistimely text presents a comprehensive guide to genetic association, a new andrapidly expanding field that aims to elucidate how our genetic code (genotypes)influences the traits we possess (phenotypes). The book provides a detailedreview of methods of gene mapping used in association with experimentalcrosses, as well as genome-wide association studies. Emphasis is placed onmodel selection procedures for analyzing data from large-scale genome scansbased on specifically designed modifications of the Bayesian informationcriterion. Features: presents a thorough introduction to the theoreticalbackground to studies of genetic association (both genetic and statistical); reviewsthe latest advances in the field; illustrates the properties of methods formapping quantitative trait loci using computer simulations and the analysis ofreal data; discusses open challenges; includes an extensive statisticalappendix as a reference for those who are not totally familiar with thefundamentals of statistics. 236 pp. Englisch. N° de réf. du vendeur 9781447173809
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Introduces the major concepts of Quantitative Trait Loci mappingDiscusses the methodology of Quantitative Trait Loci mapping in experimental populationsDescribes the methods for Genome Wide Association Studies and related multiple testing a. N° de réf. du vendeur 447761830
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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Thistimely text presents a comprehensive guide to genetic association, a new andrapidly expanding field that aims to elucidate how our genetic code (genotypes)influences the traits we possess (phenotypes). The book provides a detailedreview of methods of gene mapping used in association with experimentalcrosses, as well as genome-wide association studies. Emphasis is placed onmodel selection procedures for analyzing data from large-scale genome scansbased on specifically designed modifications of the Bayesian informationcriterion. Features: presents a thorough introduction to the theoreticalbackground to studies of genetic association (both genetic and statistical); reviewsthe latest advances in the field; illustrates the properties of methods formapping quantitative trait loci using computer simulations and the analysis ofreal data; discusses open challenges; includes an extensive statisticalappendix as a reference for those who are not totally familiar with thefundamentals of statistics. N° de réf. du vendeur 9781447173809
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Taschenbuch. Etat : Neu. Phenotypes and Genotypes | The Search for Influential Genes | Florian Frommlet (u. a.) | Taschenbuch | Computational Biology | xii | Englisch | 2019 | Springer | EAN 9781447173809 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. N° de réf. du vendeur 115102194
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Thistimely text presents a comprehensive guide to genetic association, a new andrapidly expanding field that aims to elucidate how our genetic code (genotypes)influences the traits we possess (phenotypes). The book provides a detailedreview of methods of gene mapping used in association with experimentalcrosses, as well as genome-wide association studies. Emphasis is placed onmodel selection procedures for analyzing data from large-scale genome scansbased on specifically designed modifications of the Bayesian informationcriterion. Features: presents a thorough introduction to the theoreticalbackground to studies of genetic association (both genetic and statistical); reviewsthe latest advances in the field; illustrates the properties of methods formapping quantitative trait loci using computer simulations and the analysis ofreal data; discusses open challenges; includes an extensive statisticalappendix as a reference for those who are not totally familiar with thefundamentals of statistics.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 236 pp. Englisch. N° de réf. du vendeur 9781447173809
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