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Mechanisms of Lymphocyte Activation and Immune Regulation VII: Molecular Determinants of Microbial Immunity - Couverture souple
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Synopsis
During the last decade, rapid progress has been made in the area of microbial immu- nity. New conceptual frameworks have emerged with regard to the processing and presen- tation of peptides and nonpeptide antigens from microbes, especially bacteria, to T cells in the context of classical MHC class I and nonconventional MHC I molecules. Experimen- tal models have been instrumental in defining some of these pathways for generating pro- tective immune responses against microbes, which form the basis for the design of new vaccines. New evidence has stressed the importance of innate immunity in microbial in- fections. The concept of dichotomy within T helper cells has revealed the role of these cell types in resistance and susceptibility to microbial-mediated pathology. These latest devel- opments in microbial immunity are discussed in this volume. Natural killer cell development is known to be regulated by the presence of MHC class I antigens. Receptors for MHC class I molecules on NK cells have been discovered. Interaction of these receptors with their specific ligands leads to inhibition of cytotoxicity. Vinay Kumar and colleagues review NK cell differentiation and ontogeny, and functions of NK cells in experimental animals. Lewis Lanier discusses the role of a newly discov- ered molecule, DAP 12, in KIR and other receptor-mediated signal transduction in NK cells. Eric Long describes the regulation of immune response by inhibitory receptors.
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Mechanisms of Lymphocyte Activation and Immune Regulation VII : Molecular Determinants of Microbial Immunity
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PF. Etat : New. This item is printed on demand. Brand new book, sourced directly from publisher. Dispatch time is 6-7 days from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely. N° de réf. du vendeur 6666-IUK-9781461374435
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Mechanisms of Lymphocyte Activation and Immune Regulation VII: Molecular Determinants of Microbial Immunity (Advances in Experimental Medicine and Biology, 452)
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Mechanisms of Lymphocyte Activation and Immune Regulation VII
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the last decade, rapid progress has been made in the area of microbial immu nity. New conceptual frameworks have emerged with regard to the processing and presen tation of peptides and nonpeptide antigens from microbes, especially bacteria, to T cells in the context of classical MHC class I and nonconventional MHC I molecules. Experimen tal models have been instrumental in defining some of these pathways for generating pro tective immune responses against microbes, which form the basis for the design of new vaccines. New evidence has stressed the importance of innate immunity in microbial in fections. The concept of dichotomy within T helper cells has revealed the role of these cell types in resistance and susceptibility to microbial-mediated pathology. These latest devel opments in microbial immunity are discussed in this volume. Natural killer cell development is known to be regulated by the presence of MHC class I antigens. Receptors for MHC class I molecules on NK cells have been discovered. Interaction of these receptors with their specific ligands leads to inhibition of cytotoxicity. Vinay Kumar and colleagues review NK cell differentiation and ontogeny, and functions of NK cells in experimental animals. Lewis Lanier discusses the role of a newly discov ered molecule, DAP 12, in KIR and other receptor-mediated signal transduction in NK cells. Eric Long describes the regulation of immune response by inhibitory receptors. 240 pp. Englisch. N° de réf. du vendeur 9781461374435
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Mechanisms of Lymphocyte Activation and Immune Regulation VII: Molecular Determinants of Microbial Immunity (Advances in Experimental Medicine and Biology, 452)
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Mechanisms of Lymphocyte Activation and Immune Regulation VII : Molecular Determinants of Microbial Immunity
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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - During the last decade, rapid progress has been made in the area of microbial immu nity. New conceptual frameworks have emerged with regard to the processing and presen tation of peptides and nonpeptide antigens from microbes, especially bacteria, to T cells in the context of classical MHC class I and nonconventional MHC I molecules. Experimen tal models have been instrumental in defining some of these pathways for generating pro tective immune responses against microbes, which form the basis for the design of new vaccines. New evidence has stressed the importance of innate immunity in microbial in fections. The concept of dichotomy within T helper cells has revealed the role of these cell types in resistance and susceptibility to microbial-mediated pathology. These latest devel opments in microbial immunity are discussed in this volume. Natural killer cell development is known to be regulated by the presence of MHC class I antigens. Receptors for MHC class I molecules on NK cells have been discovered. Interaction of these receptors with their specific ligands leads to inhibition of cytotoxicity. Vinay Kumar and colleagues review NK cell differentiation and ontogeny, and functions of NK cells in experimental animals. Lewis Lanier discusses the role of a newly discov ered molecule, DAP 12, in KIR and other receptor-mediated signal transduction in NK cells. Eric Long describes the regulation of immune response by inhibitory receptors. N° de réf. du vendeur 9781461374435
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Mechanisms of Lymphocyte Activation and Immune Regulation VII
Edité par
Springer US, 2012
ISBN 10 : 146137443X
ISBN 13 : 9781461374435
Neuf
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Kartoniert / Broschiert. Etat : New. Proceedings of the Seventh International Conference held in New Port Beach, California, February 6-8, 1998 Innate Defense Mechanisms: Development of Self-Recognition Systems in Natural Killer Cells P.V. Sivakumar, et al. Activating and Inhibitory NK. N° de réf. du vendeur 4195581
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Mechanisms of Lymphocyte Activation and Immune Regulation VII | Molecular Determinants of Microbial Immunity
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Taschenbuch. Etat : Neu. Mechanisms of Lymphocyte Activation and Immune Regulation VII | Molecular Determinants of Microbial Immunity | Sudhir Gupta (u. a.) | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2012 | Springer Us | EAN 9781461374435 | Verantwortliche Person für die EU: Springer Heidelberg, Tiergartenstr. 17, 69121 Heidelberg, buchhandel-buch[at]springer[dot]com | Anbieter: preigu. N° de réf. du vendeur 105997379
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