Autophagy and Cancer - Couverture rigide

Wang

Couverture rigide

ISBN 10 : 1461465605 ISBN 13 : 9781461465607

Editeur : Springer, 2013

Synopsis

With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy - what to target and how to target it. ​

A propos du livre

À propos de l?auteur

Dr. Hong-Gang Wang is the Lois High Berstler Professor, Department of Pharmacology at Penn State College of Medicine. Dr. Wang is a leading research scientist in the area of autophagy and cancer.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2013
• Langue: anglais
• ISBN 10: 1461465605
• ISBN 13: 9781461465607
• Reliure: Relié
• Nombre de pages: 276
• Coordonnées du fabricant: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Poststr. 9; Darmstadt; 64293; Allemagne