Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells - Couverture souple

9781475796872: Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

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ISBN 10 : 1475796870 ISBN 13 : 9781475796872

Editeur : Springer, 2013

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This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther- modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem- brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability(? CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener- alized and virtually all cells were thought to have a very high P Cl and a ther- modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks.

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�diteur: Springer
Date d'�dition: 2013
Langue: anglais
ISBN 10: 1475796870
ISBN 13: 9781475796872
Reliure: Broch�
Nombre de pages: 444
�diteur: Alvarez-Leefmans F.J., Russell John M.
Coordonn�es du fabricant: non disponible
Personne responsable: CMN Printpool Inh. Mathis Neumann
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9780306434266: Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

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ISBN 10 : 0306434261 ISBN 13 : 9780306434266
Editeur : Plenum Publishing Co.,N.Y., 1990
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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells (eng)

Alvarez-Leefmans, F.J.

Edit� par Springer, 2013

ISBN 10 : 1475796870 ISBN 13 : 9781475796872

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

Alvarez-Leefmans, F. J.|Russell, John M.

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracte. N� de r�f. du vendeur 4208571

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

John M. Russell

Edit� par Springer US Apr 2013, 2013

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability( CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener alized and virtually all cells were thought to have a very high P Cl and a ther modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. 444 pp. Englisch. N� de r�f. du vendeur 9781475796872

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

F. J. Alvarez-Leefmans (u. a.)

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ISBN 10 : 1475796870 ISBN 13 : 9781475796872

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

F. J. Alvarez-Leefmans

Edit� par Springer, Springer Apr 2013, 2013

ISBN 10 : 1475796870 ISBN 13 : 9781475796872

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability( CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener alized and virtually all cells were thought to have a very high P Cl and a ther modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 444 pp. Englisch. N� de r�f. du vendeur 9781475796872

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Chloride Channels and Carriers in Nerve, Muscle, and Glial Cells

F. J. Alvarez-Leefmans

Edit� par Springer, Springer, 2013

ISBN 10 : 1475796870 ISBN 13 : 9781475796872

Neuf Taschenbuch

Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne

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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - This is a book about how Cl- crosses the cell membranes of nerve, muscle, and glial cells. Not so very many years ago, a pamphlet rather than book might have resulted from such an endeavor! One might ask why Cl-, the most abundant biological anion, attracted so little attention from investigators. The main reason was that the prevailing paradigm for cellular ion homeostasis in the 1950s and 1960s assigned Cl- a ther modynamically passive and unspecialized role. This view was particularly prominent among muscle and neuroscience investigators. In searching for reasons for such a negative (no pun intended) viewpoint, it seems to us that it stemmed from two key experimental observations. First, work on frog skeletal muscle showed that Cl- was passively distributed between the cytoplasm and the extracellular fluid. Second, work on Cl- transport in red blood cells confirmed that the Cl- transmembrane distribution was thermodynamically passive and, in addition, showed that Cl- crossed the mem brane extremely rapidly. This latter finding [for a long time interpreted as being the result of a high passive chloride electrical permeability( CI)] made it quite likely that Cl- would remain at thermodynamic equilibrium. These two observations were gener alized and virtually all cells were thought to have a very high P Cl and a ther modynamically passive Cl- transmembrane distribution. These concepts can still be found in some physiology and neuroscience textbooks. N� de r�f. du vendeur 9781475796872

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