Mechanisms of Lymphocyte Activation and Immune Regulation V - Couverture souple

Couverture souple

ISBN 10 : 1489909885 ISBN 13 : 9781489909886

Editeur : Springer, 2014

Synopsis

Section I: Signaling by Antigen Receptors of B Cells.- Signaling and Internalisation Function of the B Cell Antigen Receptor Complex.- Mechanism of B Cell Antigen Receptor Function: Transmembrane Signaling and Triggering of Apoptosis.- B-Cell Activation by Wild Type and Mutant Ig-? Cytoplasmic Domains.- Accessory Molecules Which Influence Signaling Through B Lymphocyte Antigen Receptors.- Section II: Signaling by Antigen Receptors of T Cells.- Analysis of the (YXXL/I)2 Signalling Motifs Found in the Cytoplasmic Segment of the Mouse CD3-? Chain.- Molecular and Genetic Insights Into T Cell Antigen Receptor Signal Transduction.- Signal Transduction During T Cell Development.- The Regulation and Function of p21Ras in Signal Transduction by the T Cell Antigen Receptor.- Immunological Tolerance by Antigen-Induced Apoptosis of Mature T Lymphocytes.- Section III: Signaling Components of Lymphocytes.- Properties of Ca Currents Activated by T Cell Receptor Signaling.- The Role of Syk in Cell Signaling.- Nonreceptor Tyrosine Kinases in Aggregation-Mediated Cell Activation.- Control of Lymphopoiesis by Non-Receptor Protein Tyrosine Kinases.- Involvement of Nonreceptor Protein Tyrosine Kinases in Multichain Immune Recognition Receptor Signal Transduction.- Phorbol Myristate Acetate-Induced Changes in Protein Kinase C Isozymes (?, ?, and ?) in Human T Cell Subsets.- Specific CD45 Isoforms Regulate T Cell Ontogeny and Are Functionally Distinct in Modifying Immune Activation.- Cloning and Characterization of NF-ATc and NF-ATp: The Cytoplasmic Components of NF-AT.- Section IV: Signaling VIA Fc Receptors and Cytokine Receptors.- Quantitative Aspects of Receptor Aggregation.- Fc Receptor Signaling.- Proximal Signals and the Control of S-Phase Entry in Interleukin-2-Stimulated T Lymphocytes.- The IL-4 Receptor - Signaling Mechanisms.- Function of the Common ? Subunit of the GM-CSF/IL-3/IL-5 Receptors.- Section V: Molecular Basis of X-Linked Immunodeficiencies.- Sharing of a Common ? Chain, ?c, by the IL-2, IL-4, and IL-7 Receptors: Implications for X-Linked Severe Combined Immunodeficiency.- X-Linked Agammaglobulinemia and Bruton's Tyrosine Kinase.- The Role of CD40 Ligand in Human Disease.- Involvement of the Protein Tyrosine Phosphatase PTP1C in Cellular Physiology, Autoimmunity and Oncogenesis.- Contributors.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2014
• Langue: anglais
• ISBN 10: 1489909885
• ISBN 13: 9781489909886
• Reliure: Broché
• Nombre de pages: 276
• Éditeur: Gupta Sudhir, Paul William E, Defranco Anthony
• Coordonnées du fabricant: KINESIS; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; 22391; Allemagne