Kisspeptin Signaling in Reproductive Biology - Couverture souple

Couverture souple

ISBN 10 : 148999839X ISBN 13 : 9781489998392

Editeur : Springer-Verlag New York Inc., 2015

Synopsis

Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis.

Détails de l'édition

• Éditeur: Springer-Verlag New York Inc.
• Date d'édition: 2015
• Langue: anglais
• ISBN 10: 148999839X
• ISBN 13: 9781489998392
• Reliure: Broché
• Nombre de pages: 526
• Éditeur: Kauffman Alexander S., Smith Jeremy T.
• Coordonnées du fabricant: GPSR Kontakt; ProductSafety@springernature.com; ; Tiergartenstr. 17; Heidelberg; 69121; Allemagne