Duchenne Muscular Dystrophy: Methods and Protocols - Couverture rigide

Couverture rigide

ISBN 10 : 1493973738 ISBN 13 : 9781493973736

Editeur : Humana Press Inc., 2017

Synopsis

This volume explores experimental approaches used to study Duchenne muscular dystrophy (DMD), an X-linked degenerative skeletal muscle disease caused by mutations in the dystrophin gene. Including the latest progress and scientific achievements, the book covers recent discoveries achieved through in vivo gene editing which have proven to be promising in restoring dystrophin expression, at least in ameliorating skeletal muscle symptoms, and the contents focus on "Omics" techniques in gene expression, protein expression, miRNAs, and long non-coding RNA analysis, as well as experimental studies of the structural/functional changes affecting the skeletal and cardiac muscles and ongoing preclinical studies and clinical trials. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Duchenne Muscular Dystrophy: Methods and Protocols serves as a guide for researchers exploring the complicated nature of dystrophin in the hope of helping the victims of this disorder.

Détails de l'édition

• Éditeur: Humana Press Inc.
• Date d'édition: 2017
• Langue: anglais
• ISBN 10: 1493973738
• ISBN 13: 9781493973736
• Reliure: Relié
• Numéro d'édition: 1
• Nombre de pages: 299
• Éditeur: Bernardini Camilla
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne