Huntington’s Disease - Couverture rigide

Couverture rigide

ISBN 10 : 1493978241 ISBN 13 : 9781493978243

Editeur : Humana Press Inc., 2018

Synopsis

1. Stereological Methods to Quantify Cell Loss in the Huntington's Disease Human Brain

Nasim F. Mehrabi, Malvindar K. Singh-Bains, Henry J. Waldvogel, and Richard L.M. Faull

2. Assessing Autophagic Activity and Aggregate Formation of Mutant Huntingtin in Mammalian Cells

Eleanna Stamatakou, Ye Zhu, and David C. Rubinsztein

3. A Filter Retardation Assay Facilitates the Detection and Quantification of Heat-Stable, Amyloidogenic Mutant Huntingtin Aggregates in Complex Biosamples

Anne Steinhof, Franziska Schindler, Alexander Buntru, Sigrid Schnoegl, and Erich E. Wanker

4. Cellular Models: HD Patient-Derived Pluripotent Stem Cells

Charlene Geater, Sarah Hernandez, Leslie Thompson, and Virginia B. Mattis

5. Non-Mammalian Models of Huntington's Disease

Anjalika Chongtham, Brett Barbaro, Tomas Filip, Adeela Syed, Weijian Huang, Marianne R. Smith, and J. Lawrence Marsh

6. Mouse Models of Huntington's Disease

Pamela P. Farshim and Gillian P. Bates

7. Motor Assessment in Huntington's Disease Mice

Stephen B. Dunnett and Simon P. Brooks

8. Automated Operant Assessments of Huntington's Disease Mouse Models

Emma Yhnell and Andreas Heuer

9. Neurophysiological Assessment of Huntington's Disease Model Mice

Elissa J. Donzis, Sandra M. Holley, Carlos Cepeda, and Michael S. Levine

10. Murine Models of Huntington's Disease for Evaluating Therapeutics

Natalia Kosior and Blair R. Leavitt

11. Generating Excitotoxic Lesion Models of Huntington's Disease

Mariah J. Lelos and Stephen B. Dunnett

12. Large-Brained Animal Models of Huntington's Disease: Sheep

A. Jennifer Morton

13. Minipigs as Large-Brained Animal Model for Huntington's Disease: From Behavior and Imaging to Gene Therapy

Ralf Reilmann and Verena Schuldenzucker

14. Non-Human Primate Models of Huntington's Disease and Their Application in Translational Research

Romina Aron Badin

15. In Vivo Multidimensional Brain Imaging in Huntington's Disease Animal Models

Julien Flament, Philippe Hantraye, and Julien Valette

16. Magnetic Resonance Imaging in Huntington's Disease

Sarah Gregory, Rachael I. Scahill, Geraint Rees, and Sarah Tabrizi

17. Biofluid Biomarkers in Huntington's Disease

Filipe B. Rodrigues, Lauren M. B

Détails de l'édition

• Éditeur: Humana Press Inc.
• Date d'édition: 2018
• Langue: anglais
• ISBN 10: 1493978241
• ISBN 13: 9781493978243
• Reliure: Relié
• Nombre de pages: 657
• Éditeur: Precious Sophie V., Rosser Anne E., Dunnett Stephen B.
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne