Multi-target Drug Design Using Chem-bioinformatic Approaches - Couverture rigide

Couverture rigide

ISBN 10 : 1493987321 ISBN 13 : 9781493987320

Editeur : Humana Press Inc., 2018

Synopsis

Part I: Chem-Bioinformatic Tools

1. Cheminformatics Approaches to Study Drug Polypharmacology

J. Jesús Naveja, Fernanda I. Saldívar-González, Norberto Sánchez-Cruz, and José L. Medina-Franco

2. Computational Predictions for Multi-Target Drug Design

Neelima Gupta, Prateek Pandya, and Seema Verma

3. Computational Multi-Target Drug Design

Azizeh Abdolmaleki, Fereshteh Shiri, and Jahan Ghasemi

Part II: Computational Multi-Target Drug Design: Literature Reviews

4. Multi-Target Drug Design for Neurodegenerative Diseases

Marco Catto, Daniela Trisciuzzi, Domenico Alberga, Giuseppe Felice Mangiatordi, and Orazio Nicolotti

5. Molecular Docking Studies in Multi-Target Antitubercular Drug Discovery

Jéssika de Oliveira Viana, Marcus T. Scotti, and Luciana Scotti

6. Advanced Chemometric Modeling Approaches for the Design of Multi-Target Drugs against Neurodegenerative Diseases

Amit Kumar Halder, Ana S. Moura, and M. Natália Dias Soeiro Cordeiro

7. Computational Studies on Natural Products for the Development of Multi-Target Drugs

Veronika Temml and Daniela Schuster

8. Computational Design of Multi-Target Drugs against Alzheimer's Disease

Sotirios Katsamakas and Dimitra Hadjipavlou-Litina

9. Design of Multi-Target Directed Ligands as a Modern Approach for the Development of Innovative Drug Candidates for Alzheimer's Disease

Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Vanessa Silva Gontijo, Flávia Pereira Dias Viegas, Kris Simone Tranches Dias, and Claudio Viegas Jr.

Part III: Case Studies

10. Virtual Screening for Dual Hsp90/B-Raf Inhibitors

Andrew Anighoro, Luca Pinzi, Giulio Rastelli, and Jürgen Bajorath

11. Strategies for Multi-Target Directed Ligands: Application in Alzheimer's Disease (AD) Therapeutics

Sucharita Das and Soumalee Basu

12. Computational Design of Multi-Target Kinase Inhibitors

Sinoy Sugunan and Rajanikant G.K.

13. Proteochemometrics for the Prediction of Peptide Binding to Multiple HLA Class II Proteins

Ivan Dimitrov, Ventsislav Yordanov, Darren R. Flower, and Irini Doytchinova

14. Linked Open Data: Ligand-Transporter Interaction Profiling and Beyond

Stefanie Kickinger, Eva Hellsberg, Sankalp Jain, and Gerhard F. Ecker

15. Design of Novel Dual Target Hits against Malaria and Tuberculosis Using Computational Docking

A propos du livre

À propos de l?auteur

Dr. Kunal Roy is a Professor in the Department of Pharmaceutical Technology, Jadavpur University, Kolkata, India. He has been a recipient of Commonwealth Academic Staff Fellowship (University of Manchester, 2007) and Marie Curie International Incoming Fellowship (University of Manchester, 2013). The field of his research interest is QSAR and Molecular Modeling with application in Drug Design and Ecotoxicological Modeling. Dr. Roy has published more than 280 research articles in refereed journals (current SCOPUS h index 37). He has also coauthored two QSAR-related books, edited three QSAR books and published ten book chapters. Dr. Roy serves in different capacities in the Editorial Boards of several International Journals.

Détails de l'édition

• Éditeur: Humana Press Inc.
• Date d'édition: 2018
• Langue: anglais
• ISBN 10: 1493987321
• ISBN 13: 9781493987320
• Reliure: Relié
• Nombre de pages: 563
• Éditeur: Roy Kunal
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible