Computational Methods for Drug Repurposing - Couverture rigide

Couverture rigide

ISBN 10 : 1493989545 ISBN 13 : 9781493989546

Editeur : Humana Press Inc., 2018

Synopsis

1. Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing

E. Sila Ozdemir, Farideh Halakou, Ruth Nussinov, Attila Gursoy, and Ozlem Keskin

2. Performing an In Silico Repurposing of Existing Drugs by Combining Virtual Screening and Molecular Dynamics Simulation

Farzin Sohraby, Milad Bagheri, and Hassan Aryapour

3. Repurposing Drugs Based on Evolutionary Relationships between Targets of Approved Drugs and Proteins of Interest

Sohini Chakraborti, Gayatri Ramakrishnan, and Narayanaswamy Srinivasan

4. Drug Repositioning by Mining Adverse Event Data in ClinicalTrials.gov

Eric Wen Su

5. Transcriptomic Data Mining and Repurposing for Computational Drug Discovery

Yunguan Wang, Jaswanth Yella, and Anil G. Jegga

6. Network-Based Drug-Repositioning: Approaches, Resources, and Research Directions

Salvatore Alaimo and Alfredo Pulvirenti

7. A Computational Bipartite-Graph-Based Drug Repurposing Method

Si Zheng, Hetong Ma, Jiayang Wang, and Jiao Li

8. Implementation of a Pipeline Using Disease-Disease Associations for Computational Drug Repurposing

Preethi Balasundaram, Rohini Kanagavelu, Nivya James, Sayoni Maiti, Shanthi Veerappapillai, and Ramanathan Karuppaswamy

9. An Application of Computational Drug Repurposing Based on Transcriptomic Signatures

Evangelos Karatzas, George Kolios, and George M. Spyrou

10. Drug-Induced Expression-Based Computational Repurposing of Small Molecules Affecting Transcription Factor Activity

Kaitlyn Gayvert and Olivier Elemento

11. A Drug Repurposing Method Based on Drug-Drug Interaction Networks and Using Energy Model Layouts

Mihai Udrescu and Lucreția Udrescu

12. Integrating Biological Networks for Drug Target Prediction and Prioritization

Xiao Ji, Johannes M. Freudenberg, and Pankaj Agarwal

13. Using Drug Expression Profiles and Machine Learning Approach for Drug Repurposing

Kai Zhao and Hon-Cheong So

14. Computational Prediction of Drug-Target Interactions via Ensemble Learning

Ali Ezzat, Min Wu, Xiaoli Li, and Chee-Keong Kwoh

15. A Machine-Learning-Based Drug Repurposing Approach Using Baseline Regularization

Zhaobin Kuang, Yujia Bao, James Thomson, Michael Caldwell, Peggy Peissig, Ron Stewart, Rebecca Willett, and David Page

16. Machine Learning Approach for Predicting New Uses of Existing Drugs and Evaluation of Their Reliabilities

Détails de l'édition

• Éditeur: Humana Press Inc.
• Date d'édition: 2018
• Langue: anglais
• ISBN 10: 1493989545
• ISBN 13: 9781493989546
• Reliure: Relié
• Nombre de pages: 343
• Éditeur: Vanhaelen Quentin
• Coordonnées du fabricant: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne