Preface...Table of Contents...Contributing Authors...
Part I Modeling
1. Agent-Based Modeling to Delineate Spatiotemporal Control Mechanisms of the Stem Cell NicheRobert Mines, Kai-Yuan Chen, and Xiling Shen
2. Modeling Cellular Differentiation and Reprogramming with Gene Regulatory NetworksAndrás Hartmann, Srikanth Ravichandran, and Antonio del Sol
3. Cell Population Model to Track Stochastic Cellular Decision-Making during Differentiation Keith Task and Ipsita Banerjee
4. Automated Formal Reasoning to Uncover Molecular Programs of Self-RenewalSara-Jane Dunn
5. Mathematical Modeling of Clonal Stem Cell DynamicsPhilip Greulich
6. Computational Tools for Quantifying Concordance in Single Cell FateJ.A. Cornwell and R.E. Nordon
7. Quantitative Modeling of the Waddington Epigenetic LandscapeAtefeh Taherian Fard and Mark A. Ragan
8. Modeling Gene Networks to Understand Multistability in Stem CellsDavid Menn and Xiao Wang
Part II Single Cell Approaches
9. Trajectory Algorithms to Infer Stem Cell Fate DecisionsEdroaldo Lummertz da Rocha and Mohan Malleshaiah
10. Gene Regulatory Networks from Single Cell Data for Exploring Cell Fate DecisionsThalia E. Chan, Michael P.H. Stumpf, and Ann C. Babtie
11. Reconstructing Gene Regulatory Networks that Control Hematopoietic CommitmentFiona K. Hamey and Berthold Göttgens
12. Investigating Cell Fate Decisions with ICGS Analysis of Single CellsNathan Salomonis
13. Lineage Inference and Stem Cell Identity Prediction using Single Cell RNA-Sequencing DataSagar and Dominic Grün
Part III Metabolism
14. Dynamic Network Modeling of Stem Cell MetabolismFangzhou Shen, Camden Cheek, and Sriram Chandrasekaran
15. Metabolomics in Stem Cell Biology ResearchSun Zhen, Jing Zhao, Hua Yu, Chenyang Zhang, Hu Li, Zhongda Zeng, and Jin Zhang
Part IV Assessing and Improving Cell Fate Engineering
16. Molecular Interaction Networks to Select Factors for Cell ConversionJohn F. Ouyang, Uma S. Kamaraj, Jose M. Polo, Julian Gough, and Owen J. L. Rackham
17. A Computational Approach for Cell Fate ReprogrammingHussein M. Abdallah and Domitilla Del Vecchio
18. Computational Analysis of Aneuploidy in Pluripotent Stem CellsUri Weissbein
19. Cell Fate Engineering Tools for iPSC Disease ModelingEmily K. W. Lo and Patrick Cahan
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume details methods and protocols to further the study of stem cells within the computational stem cell biology (CSCB) field. Chapters are divided into four sections covering the theory and practice of modeling of stem cell behavior, analyzing single cell genome-scale measurements, reconstructing gene regulatory networks, and metabolomics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Computational Stem Cell Biology: Methods and Protocols will be an invaluable guide to researchers as they explore stem cells from the perspective of computational biology. 472 pp. Englisch. N° de réf. du vendeur 9781493992232
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