Chimeric RNA: Methods and Protocols - Couverture souple

 
9781493999064: Chimeric RNA: Methods and Protocols

Synopsis

This book provides numerous methods for identification, validation, and functional characterization of chimeric RNAs, herein described as any transcript which contains the nucleotide sequence of two distinct parental genes. Beginning with identification and characterization through bioinformatics tools, the book continues with experimental validation using RT-PCR, hybridization methods for RNA, and the use of mass spectrometry data for fusion protein validation, as well as functional and mechanistic studies of chimeric RNAs and translational applications. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, Chimeric RNA: Methods and Protocols is an ideal guide to this expansive field and an inspiration to researchers seeking to further our knowledge of these remarkable features of the transcriptome.

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Autres éditions populaires du même titre

9781493999033: Chimeric Rna: Methods and Protocols

Edition présentée

ISBN 10 :  1493999036 ISBN 13 :  9781493999033
Editeur : Humana Press Inc., 2019
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