Articles liés à Antibody-Drug Conjugates: Methods and Protocols

Antibody-Drug Conjugates: Methods and Protocols - Couverture souple

 
9781493999316: Antibody-Drug Conjugates: Methods and Protocols

Synopsis

This volume looks at key methodologies that are commonly used across antibody drug conjugates (ADCs) programs. The chapters in this book cover topics such as conjugations to endogenous cysteine residues; click chemistry conjugations; antibody conjugations via glycosyl remodeling; analysis of ADCs by native mass spectrometry; characterization of ADCs by capillary electrophoresis; LC/MS methods for studying lysosomal ADC catabolism; and determination of ADC concentration by ligand-binding assays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Antibody-Drug Conjugates: Methods and Protocols is a valuable resource that aims to lower the “activation barrier” when undertaking a new discipline, and provides a “toolbox” for the next generation of ADC scientists.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Autres éditions populaires du même titre

9781493999286: Antibody-Drug Conjugates: Methods and Protocols

Edition présentée

ISBN 10 :  1493999281 ISBN 13 :  9781493999286
Editeur : Humana Press Inc., 2019
Couverture rigide