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Studies on the mechanism of binding of 99Tc-MDP to human serum albumin: Isotopes in Medicine - Couverture souple

AL-Mudhaffar Dr., Prof Sami A.

 
9781522930556: Studies on the mechanism of binding of 99Tc-MDP to human serum albumin: Isotopes in Medicine
Couverture souple
ISBN 10 : 1522930558 ISBN 13 : 9781522930556
Editeur : CreateSpace Independent Publishing Platform, 2015

Synopsis

This book deals with the binding of 99mTc-MDP to the bone binding protein (BBP). The specificity of 99mTc-MDP binding to the (BBP) was examined, the results show that the non specific binding was 8-12% of the total binding. The effect of mono and divalent chloride salts were also examined.The optimum pH for the binding was 7.4, the most suitable amounts of MDP concentration to give maximum binding was 2.8x10-6m. the association constant Ka and maximum binding capacities Bmax of 99mTc-MDP to its binding sites was determined from scatchard plots. The results revealed that Ka and Bmax values were temperature dependent.

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Éditeur
CreateSpace Independent Publishing Platform
Date d'édition
2015
Langue
anglais
ISBN 10 
1522930558
ISBN 13 
9781522930556
Reliure
Broché
Numéro d'édition
1
Nombre de pages
196
Coordonnées du fabricant
Printed by Amazon on behalf of the author
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