A concise guide to mathematical modeling and analysis of pharmacokinetic data, this book covers methods for maximizing the information obtained from given data. It presents a systematic approach to using the mathematical software tools available so that the investigator may extract the maximum information from a given set of data. The author discusses the rationale for mathematical modeling and presents a brief review of pharmacokinetic models to provide a common framework for the following chapters. It describes questions of experimental design and covers topics such as pilot study considerations, identifiability of parameter values, and optimal sampling time selection.
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Bourne, DavidW.A.
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Vendeur : Ammareal, Morangis, France
Hardcover. Etat : Très bon. Ancien livre de bibliothèque avec équipements. Edition 1995. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 1995. Ammareal gives back up to 15% of this item's net price to charity organizations. N° de réf. du vendeur H-696-023
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Vendeur : Blindpig Books, Salt lake city, UT, Etats-Unis
hardcover. Etat : Good. 1. some light wear. no jacket. Good copy. N° de réf. du vendeur 24-05-14-gw-32290-lcz
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Vendeur : Fox and Tome Books, Frederick, MD, Etats-Unis
Hardback. Etat : Fine. In excellent condition, no writing or markings, book is crisp and clean. 100% satisfaction guarantee. Shipped with care in a bubble mailer. Feel free to inquire for photos or more details. I hand inspect every item. --- A concise treatment of fitting mathematical models to pharmacokinetic data, by Steven Strauss and David W.A. Bourne. The opening chapters explain why data are modeled at all: to condense results, test mechanisms and make predictions. They then set out a general fitting method. The authors cover compartmental, physiologically based and pharmacodynamic models, and show how to simulate data from explicit and implicit equations and from differential equations, using Laplace transforms or numerical integration. Later chapters deal with getting initial parameter estimates through graphical methods, linear regression, curve stripping, area-under-the-curve estimation and deconvolution. They also cover non-linear regression algorithms, including grid search, steepest descent, Gauss-Newton and simplex, along with the problem of local minima. Weighting schemes range from equal weights to extended least squares and Bayesian methods, and population data are also treated. The book closes with chapters on reading program output and on experimental design. N° de réf. du vendeur OA-240115-shelf-18-050
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Vendeur : MB Books, Derbyshire, Royaume-Uni
Hardcover. Etat : Good. No Jacket. 1st Edition. Condition : Good. Hard cover, no jacket. 139pp. Former university library copy with associated markings. No annotations or highlighting to text. THICK LIBRARY TAPE ACROSS COVERS. Photo on request. N° de réf. du vendeur 943168
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Vendeur : Corner of a Foreign Field, Tokyo, TOKYO, Japon
Hardcover. Etat : Fine. No Jacket. 1995.Hardcover.Fine.Tiny blemish to lower back corner otherwise as new.Ships from Japan.Usually ships in 1-2 working days. N° de réf. du vendeur 73
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Vendeur : thebookforest.com, San Rafael, CA, Etats-Unis
Etat : Like New. Page block firm and clean, binding unblemished, boards straight, no markings of any kind. Fine, like new condition. Well packaged and promptly shipped from California. Partnered with Friends of the Library since 2010. N° de réf. du vendeur BAY_05_SH_031237
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Vendeur : SHIMEDIA, Brooklyn, NY, Etats-Unis
Etat : New. Satisfaction Guaranteed or your money back. N° de réf. du vendeur 1566762049
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Vendeur : BennettBooksLtd, Los Angeles, CA, Etats-Unis
hardcover. Etat : New. In shrink wrap. Looks like an interesting title! N° de réf. du vendeur Q-1566762049
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Vendeur : BUCHSERVICE / ANTIQUARIAT Lars Lutzer, Wahlstedt, Allemagne
Hardcover. Etat : gut. 1995. Mathematical Modeling of Pharmacokinetic Data In englischer Sprache. pages. N° de réf. du vendeur BN509410
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Vendeur : moluna, Greven, Allemagne
Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Bourne, DavidW.A.A concise guide to mathematical modeling and analysis of pharmacokinetic data, this book contains valuable methods for maximizing the information obtained from given data. It is an ideal resource for scientists, scholars, and advanced s. N° de réf. du vendeur 596325812
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