Cell Injury - Couverture souple

Lee, Raphael C.

Couverture souple

ISBN 10 : 1573316172 ISBN 13 : 9781573316170

Editeur : John Wiley & Sons, 2006

Synopsis

When cells are damaged, as often occurs during trauma and metabolic stress, a highly evolved cell healing process follows that was designed to enhance cell survival or remove irreparably injured cells. Following injury, cells attempt to seal breaks in their membranes, chaperone removal or refolding of altered proteins, repair damaged DNA, or if necessary commit to programmed cell death.

When cell injury is too extensive to permit reparative responses, acute cellular necrosis or apoptosis can result. Understanding injury at the subcellular organelle and molecular levels is essential for development of new therapeutic strategies and for optimal management of injured victims.

In this volume, various modes of injury that can occur are described, as well as the basic molecular healing responses and pathways of metabolic survival or death. The approach taken here is to look at these processes at the cellular and subcellular levels, rather than at the tissue level, and this volume will be a valuable resource to anyone interested in wound healing, biological stress responses, molecular chaperones, radiobiology, biomechanics, and biomedical engineering, as well as trauma and critical care medicine.

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A propos du livre

À propos de l'auteur

Raphael Carl Lee is an American surgeon, medical researcher, biomedical engineer, and entrepreneur. Kimm J. Hamann is the editor of Cell Injury: Mechanisms, Responses, and Therapeutics, Volume 1066, published by Wiley.

Détails de l'édition

• Éditeur: John Wiley & Sons
• Date d'édition: 2006
• Langue: anglais
• ISBN 10: 1573316172
• ISBN 13: 9781573316170
• Reliure: Broché
• Nombre de pages: 340
• Coordonnées du fabricant: non disponible
• Personne responsable: Wiley-VCH GmbH; product_safety@wiley.com; ; Boschstrasse 12; Weinheim; 69469; Allemagne