Animal Models: Their Value in Predicting Drug Efficacy and Toxicity - Couverture souple

Couverture souple

ISBN 10 : 1573318752 ISBN 13 : 9781573318754

Editeur : New York Academy of Sciences, 2012

Synopsis

The Global Medical Excellence Cluster (GMEC) and the New York Academy of Sciences, in collaboration with Imperial College London and King's College London, sponsored the conference "Animal Models and Their Value in Predicting Drug Efficacy and Toxicity." The goal was to provide a neutral forum to critically examine and discuss the traditional role of pre-clinical animal models in drug discovery, and how these models most effectively contribute to translational medicine and therapeutic development.

International, multi-disciplinary clinical and basic science investigators convened to discuss and identify changes needed to increase the predictive power of various models for drug efficacy and toxicity in humans, and ways in which to further refine, reduce, and replace animal models in biomedical research in areas such as metabolic and cardiovascular disease, inflammation, pain. Other topics discussed included new technologies in bioimaging, biosimulation, bioinformatics, the generation of genetically modified animals, phenotype screening, alternatives to rodent models, the use of embryonic stem cells, patient-specific induced pluripotent stem cells, and humanized animal models. This volume presents a collection of short papers on some of the topics discussed at this important conference.

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A propos du livre

À propos de l?auteur

For 200 years--since 1817--the Academy has brought together extraordinary people working at the frontiers of discovery. Among the oldest scientific organizations in the United States, it has become not only an enduring cultural institution in New York, but also one of the most significant organizations in the global scientific community.

Détails de l'édition

• Éditeur: New York Academy of Sciences
• Date d'édition: 2012
• Langue: anglais
• ISBN 10: 1573318752
• ISBN 13: 9781573318754
• Reliure: Broché
• Numéro d'édition: 1
• Nombre de pages: 96
• Éditeur: Editorial Staff Of Annals Of The New York Academy Of Sciences
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible