Cancer Diagnostics: Current and Future Trends - Couverture rigide

Couverture rigide

ISBN 10 : 1588291677 ISBN 13 : 9781588291677

Editeur : Humana Press Inc., 2004

Synopsis

In the past, many tumor marker laboratory tests have not been sensitive enough for the very early detection of cancer. However, many of them have nonetheless proved useful in monitoring therapy, following the course of the tumor, and predicting prog- nosis. Today, cancer may be viewed as a genetic disease with various specific chromo- somal and nucleotide aberrations, such as mutations, deletions, gene amplification, gene rearrangements, and translocations occurring during the transformation of a nor- mal cell into a malignant cell. The considerable advances in technology during the past several years have greatly enhanced our ability to detect human cancers in the very early stages of tumor forma- tion. These technologies include: (1) nucleotide molecular assays (genomics); (2) proteomics (multiplex protein measurements); (3) DNA microarrays; and (4) bio- informatics. Many of these technologies are already helping in the integration and use of multiple biomarkers for tumors. Although the individual biomarkers may reveal only limited information, the use of multiple biomarkers can help markedly elevate the diagnostic capabilities for early detection of tumors.

Détails de l'édition

• Éditeur: Humana Press Inc.
• Date d'édition: 2004
• Langue: anglais
• ISBN 10: 1588291677
• ISBN 13: 9781588291677
• Reliure: Relié
• Nombre de pages: 519
• Éditeur: Nakamura Robert M., Grody Wayne W., Wu James T., Nagle Raymond B.
• Coordonnées du fabricant: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Tiergartenstr. 17; Heidelberg; 69121; Allemagne