Cardiac Gene Expression: Methods And Protocols - Couverture rigide

Couverture rigide

ISBN 10 : 1588293521 ISBN 13 : 9781588293527

Editeur : Humana Press Inc., 2007

Synopsis

Cardiac Gene Expression: Methods and Protocols presents both cutting-edge and established methods for studying cardiac gene expression. The protocols provide a template for solid research, and cover the process through screening, analysis, characterization, and functional confirmation of novel genes or known genes with a new function.

Section I, Cardiac Gene Expression Profiling: The Global Perspective, discusses several different approaches to examining, identifying, and analyzing changes in transcriptome gene expression. Section II, Cardiac Gene Regulation: Gene-Specific mRNA Measurement in the Myocardium, outlines more sensitive and gene-targeted expression methods. Section III, Cardiac Gene Regulation: Promoter Characterization in the Myocardium, provides protocols for the study of underlying gene regulation mechanisms by focusing on the interaction of transcription factors with their cognate cis binding elements. Section IV, In Silico Assessment of Regulatory cis-Elements and Gene Regulation, and Section V, Cardiac Single Network Polymorphisms, emphasize new analytical approaches for deciphering the functional elements buried in the 3 billion nucleotides of the human genome and other model genomes. The concluding section, Gene Overexpression and Targeting in the Myocardium, highlights methods that facilitate overexpression or cardiac-specific targeted gene deletion.

A propos du livre

Présentation de l'éditeur

This book presents both cutting-edge and established methods for studying cardiac gene expression. The protocols provide a template for solid research, and cover the process through screening, analysis, characterization, and functional confirmation of novel genes or known genes with a new function. The concluding section of the book highlights methods that facilitate overexpression or cardiac-specific targeted gene deletion.

Détails de l'édition

• Éditeur: Humana Press Inc.
• Date d'édition: 2007
• Langue: anglais
• ISBN 10: 1588293521
• ISBN 13: 9781588293527
• Reliure: Relié
• Nombre de pages: 366
• Éditeur: Zhang Jun, Rokosh Gregg
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible