Dictyostelium Discoideum Protocols - Couverture rigide

Couverture rigide

ISBN 10 : 1588296237 ISBN 13 : 9781588296238

Editeur : Humana Press Inc., 2006

Synopsis

Dictyostelium discoideum is a simple but fascinating eukaryotic microorg- ism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as independent single cells. Exhaustion of the bacterial food source triggers a developmental program, in which up to 100,000 cells aggregate by chemotaxis towards cAMP. Morphogenesis and cell different- tion then culminate in the production of spores enabling the organism to survive unfavorable conditions. Dictyostelium offers unique advantages for studying f- damental cellular processes with the aid of powerful molecular genetic, bioche- cal, and cell biological tools. These processes include signal transduction, chemotaxis, cell motility, cytokinesis, phagocytosis, and aspects of development such as cell sorting, pattern formation and cell type differentiation. Recently, D- tyostelium was also described as a suitable host for pathogenic bacteria in which one can conveniently study the process of infection. In addition, Dictyostelium has many of the experimental conveniences of Saccharomyces cerevisiae and is pr- ably the best experimentally manipulatable protozoan, providing insight into this diverse group of organisms, which includes some of the most dangerous human parasites. The recent completion of the Dictyostelium genome sequencing project strengthens the position of D. discoideum as a model organism. The completed genome sequence and other valuable community resources constitute the source for basic biological and biomedical research and for genome-wide analyses.

A propos du livre

Présentation de l'éditeur

The book offers an introduction to the amoebozoa, presents large-scale analysis methods made possible by the completion of the Dictyostelium genome sequence, and details molecular genetics techniques, cell biological, biochemical and biophysical methods.

Détails de l'édition

• Éditeur: Humana Press Inc.
• Date d'édition: 2006
• Langue: anglais
• ISBN 10: 1588296237
• ISBN 13: 9781588296238
• Reliure: Relié
• Nombre de pages: 564
• Éditeur: Eichinger Ludwig
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible