Several genetic and pathogenic diseases are described to illustrate how diseases can and do disrupt normal molecular and cellular functions, and how those disruptions affect entire organisms. In the case of genetic diseases, how they arise and are maintained in populations is discussed. In the case of pathogenic and parasitic organisms, understanding their complex life cycles and their modes of transmission is critical to understanding their effects on individuals and how disease outbreaks occur in ecological systems. Communication between the pathogen and the host organism occurs in the course of infection and involves the disruption of normal cell function. Finally, epidemiology is briefly discussed, using the case of severe acute respiratory syndrome (SARS). Data are used to describe how the disease may have originated and evolved to infect humans, and how it spread relatively quickly and almost caused a global pandemic. Understanding how disease outbreaks occur in ecological systems is critical to controlling the spread of disease.
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Christopher Paradise is professor of biology and environmental studies at Davidson College. He teaches introductory biology, ecology, entomology, and topical seminars on ecotoxicology and renewable natural resources. He also occasionally leads a study abroad program in India. His research evaluates anthropogenic factors that influence insect biodiversity at a variety of scales. His current research interests include effects of land use patterns on pollinator communities in parks.
A. Malcolm Campbell teaches biology at Davidson College, NC. He received national and international education awards: Genetics Society of America (2013); American Association for the Advancement of Science (2012); and American Society for Cell Biology (2006). He was the founding co-editor in chief of CBE Life Sciences Education; founding director of Genome Consortium for Active Teaching (GCAT); and member of the American Society for Cell Biology governing council (2012 –2014).
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