Articles liés à Cocaine's Impact on Affect, Activity, and Reward...

Cocaine's Impact on Affect, Activity, and Reward Are Dose-Dependently Impacted by Age - Couverture rigide

Kelley, Brian M; Perry, Candace E; Hershey, Hillary A; Baird, Adrianna L

 
9781611227444: Cocaine's Impact on Affect, Activity, and Reward Are Dose-Dependently Impacted by Age
Couverture rigide
ISBN 10 : 1611227445 ISBN 13 : 9781611227444
Editeur : Nova Science Publishers Inc, 2011

Synopsis

This book examines the impact of different doses of cocaine on three interrelated measures related to affective behaviours between adolescent and adult mice in order to assess the range of affective and rewarding responses, measure of despair, activity, and reward were used. Such methods included the forced swim test (FST), motor activity (MA), and the conditioned place preference (CPP) tests, respectively. Cocaine was selected, in part, because of its robust psychostimulant properties, its use by millions of substance abusers world-wide, and its well understood mechanism of action. This study may help explain some of the neurobiological underpinnings of these finding because cocaine was especially effective in reducing despair-related behaviour in adolescence compared with adults, yet less effective in as an euphoric agent.

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Éditeur
Nova Science Publishers Inc
Date d'édition
2011
Langue
anglais
ISBN 10 
1611227445
ISBN 13 
9781611227444
Reliure
Relié
Nombre de pages
42
Coordonnées du fabricant
non disponible
Personne responsable
non disponible