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The IGF System: Molecular Biology, Physiology, and Clinical Applications - Couverture souple
Livre 8 sur 84: Contemporary Endocrinology
Synopsis
It has been over 40 years since the original report by Salmon and Daughaday demon- strating that the ability of GH to stimulate sulfation of cartilage was mediated by a "sulfation factor. " In the ensuing decades, it has become apparent that this "sulfation factor activity" encompasses a complex system ofligands (IGFs), receptors, and carrier proteins that are, in tum, responsible for a wide array of cellular actions. The IGF system has been demonstrated to be critically involved in both intrauterine and postnatal growth, and to have important implications in cancer biology as well, owing to the ability of the IGFs to function in endocrine, paracrine, and autocrine modes and given the wide distri- bution of IGFs in virtually every organ system. The contributions to The /GF System reflect the wide span of interest in the IGF system and its implications for normal and abnormal growth and metabolism. The chapters have been divided into four broad sections: I. Molecular biology of the IGF system; II. Bio- logical actions of the IGFs; III. IGF physiology; and IV. Clinical aspects of the IGFs. We have made every effort to highlight the major contemporary themes in IGF biology, but as is inevitable in such a fast-moving field, perspectives will continue to change as new information is accumulated.
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The IGF System (eng)
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The IGF System
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The IGF System
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It has been over 40 years since the original report by Salmon and Daughaday demon strating that the ability of GH to stimulate sulfation of cartilage was mediated by a 'sulfation factor. ' In the ensuing decades, it has become apparent that this 'sulfation factor activity' encompasses a complex system ofligands (IGFs), receptors, and carrier proteins that are, in tum, responsible for a wide array of cellular actions. The IGF system has been demonstrated to be critically involved in both intrauterine and postnatal growth, and to have important implications in cancer biology as well, owing to the ability of the IGFs to function in endocrine, paracrine, and autocrine modes and given the wide distri bution of IGFs in virtually every organ system. The contributions to The /GF System reflect the wide span of interest in the IGF system and its implications for normal and abnormal growth and metabolism. The chapters have been divided into four broad sections: I. Molecular biology of the IGF system; II. Bio logical actions of the IGFs; III. IGF physiology; and IV. Clinical aspects of the IGFs. We have made every effort to highlight the major contemporary themes in IGF biology, but as is inevitable in such a fast-moving field, perspectives will continue to change as new information is accumulated. 804 pp. Englisch. N° de réf. du vendeur 9781617371387
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The IGF System | Molecular Biology, Physiology, and Clinical Applications
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Taschenbuch. Etat : Neu. The IGF System | Molecular Biology, Physiology, and Clinical Applications | Ron G. Rosenfeld (u. a.) | Taschenbuch | Contemporary Endocrinology | xii | Englisch | 2010 | Humana | EAN 9781617371387 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. N° de réf. du vendeur 107146772
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The IGF System: Molecular Biology, Physiology, and Clinical Applications (Contemporary Endocrinology, 17)
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Igf System : Molecular Biology, Physiology, and Clinical Applications
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The IGF System
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -It has been over 40 years since the original report by Salmon and Daughaday demon strating that the ability of GH to stimulate sulfation of cartilage was mediated by a 'sulfation factor. ' In the ensuing decades, it has become apparent that this 'sulfation factor activity' encompasses a complex system ofligands (IGFs), receptors, and carrier proteins that are, in tum, responsible for a wide array of cellular actions. The IGF system has been demonstrated to be critically involved in both intrauterine and postnatal growth, and to have important implications in cancer biology as well, owing to the ability of the IGFs to function in endocrine, paracrine, and autocrine modes and given the wide distri bution of IGFs in virtually every organ system. The contributions to The /GF System reflect the wide span of interest in the IGF system and its implications for normal and abnormal growth and metabolism. The chapters have been divided into four broad sections: I. Molecular biology of the IGF system; II. Bio logical actions of the IGFs; III. IGF physiology; and IV. Clinical aspects of the IGFs. We have made every effort to highlight the major contemporary themes in IGF biology, but as is inevitable in such a fast-moving field, perspectives will continue to change as new information is accumulated.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 804 pp. Englisch. N° de réf. du vendeur 9781617371387
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The IGF System : Molecular Biology, Physiology, and Clinical Applications
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Taschenbuch. Etat : Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - It has been over 40 years since the original report by Salmon and Daughaday demon strating that the ability of GH to stimulate sulfation of cartilage was mediated by a 'sulfation factor. ' In the ensuing decades, it has become apparent that this 'sulfation factor activity' encompasses a complex system ofligands (IGFs), receptors, and carrier proteins that are, in tum, responsible for a wide array of cellular actions. The IGF system has been demonstrated to be critically involved in both intrauterine and postnatal growth, and to have important implications in cancer biology as well, owing to the ability of the IGFs to function in endocrine, paracrine, and autocrine modes and given the wide distri bution of IGFs in virtually every organ system. The contributions to The /GF System reflect the wide span of interest in the IGF system and its implications for normal and abnormal growth and metabolism. The chapters have been divided into four broad sections: I. Molecular biology of the IGF system; II. Bio logical actions of the IGFs; III. IGF physiology; and IV. Clinical aspects of the IGFs. We have made every effort to highlight the major contemporary themes in IGF biology, but as is inevitable in such a fast-moving field, perspectives will continue to change as new information is accumulated. N° de réf. du vendeur 9781617371387
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Igf System : Molecular Biology, Physiology, and Clinical Applications
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Humana, 2010
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ISBN 13 : 9781617371387
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The IGF System. Molecular Biology, Physiology, and Clinical Applications.
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Humana Press Inc., 2010
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Etat : New. Editor(s): Rosenfeld, Ron G.; Roberts, Charles. Series: Contemporary Endocrinology. Num Pages: 800 pages, biography. BIC Classification: MJG. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 40. Weight in Grams: 1369. . 2010. 1st ed. Softcover of orig. ed. 1999. Paperback. . . . . N° de réf. du vendeur V9781617371387
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