Fluoropyrimidines in Cancer Therapy - Couverture souple

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9781617372742: Fluoropyrimidines in Cancer Therapy

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ISBN 10 : 1617372749 ISBN 13 : 9781617372742

Editeur : Humana Press, 2010

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Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents.

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�diteur: Humana Press
Date d'�dition: 2010
Langue: anglais
ISBN 10: 1617372749
ISBN 13: 9781617372742
Reliure: Broch�
Nombre de pages: 340
�diteur: Rustum Youcef M.
Coordonn�es du fabricant: Springer Nature Customer Service Center GmbH
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Fluoropyrimidines in Cancer Therapy

Youcef M. Rustum

Edit� par Humana Press Nov 2010, 2010

ISBN 10 : 1617372749 ISBN 13 : 9781617372742

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents. Although the action of the standard chemotherapeutic agent for the treatment of advanced colorectal cancer (5-fluorouracil or 5-FU) was improved significantly by combining it with leucovorin (LV), the improved response rate was associated with significant side-effects in approximately thirty percent of patients. In Fluoropyrimidines in Cancer Therapy, leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU, with and without LV and its prodrugs, in the treatment of colorectal cancer. Among the combination agents considered are Orzel (UFT/LV), 5-FU/Eniluracil (5-FU/EU), capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on the historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents. Authoritative and integrative, Fluoropyrimidines in Cancer Therapy summarizes the latest preclinical and clinical experiences using fluoropyrimidines to treat colorectal cancer, delineates the underlying mechanisms and choices for therapy, describes the ongoing search to identify ever more effective and selective agents with novel mechanisms of action, and details the development of new mechanism-based combination therapies. 340 pp. Englisch. N� de r�f. du vendeur 9781617372742

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Fluoropyrimidines in Cancer Therapy (Cancer Drug Discovery and Development)

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Fluoropyrimidines in Cancer Therapy

Rustum, Youcef M.

Edit� par Humana Press, 2010

ISBN 10 : 1617372749 ISBN 13 : 9781617372742

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV. N� de r�f. du vendeur 4256751

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Fluoropyrimidines in Cancer Therapy

. Ed(s): Rustum, Youcef M.

Edit� par Humana Press Inc., 2010

ISBN 10 : 1617372749 ISBN 13 : 9781617372742

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Etat : New. Editor(s): Rustum, Youcef M. Series: Cancer Drug Discovery and Development. Num Pages: 326 pages, biography. BIC Classification: MJCL. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 18. Weight in Grams: 647. . 2010. 1st ed. Softcover of orig. ed. 2003. Paperback. . . . . N� de r�f. du vendeur V9781617372742

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Fluoropyrimidines in Cancer Therapy

Youcef M. Rustum

Edit� par Humana Press, 2010

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Fluoropyrimidines in Cancer Therapy

Youcef M. Rustum

Edit� par Humana Press, Humana Press Nov 2010, 2010

ISBN 10 : 1617372749 ISBN 13 : 9781617372742

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 340 pp. Englisch. N� de r�f. du vendeur 9781617372742

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