Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of synaptic function in the nervous system, and shows how alterations in lipid raft metabolism are implicated in the pathogenesis of neurodegenerative disorders. Techniques are also described for the isolation of lipid rafts, the analysis of the lipid and protein components of lipid rafts, the imaging of lipid rafts in living cells, and the analysis of signal transduction in lipid rafts.
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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Lipid rafts-discrete regions in cell membranes that are rich in cholesterol and sphingolipids-are emerging not only as pivotal command and control centers for cellular signaling processes, but also as central to a wide array of human diseases, including immune disorders, diabetes, cardiovascular disease, and Alzheimer's disease. In Membrane Microdomain Signaling: Lipid Rafts in Biology and Medicine, multidisciplinary experts offer cutting-edge reviews of our current understanding of these membrane microdomains and their physiological and pathological roles. Here, readers will discover how lipid rafts change in cells over time and how they respond to various environmental signals, how cholesterol modulates the signaling function of lipid rafts, and how lipid rafts, the extracellular matrix, and the cell cytoskeleton structurally interact. Also described are the role of lipid rafts in learning, memory, and cancer, and as portals for endocytic uptake of an anticancer- and apoptotic alkyl-lysophospholipid. The authors also present emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of synaptic function in the nervous system, and that alterations in lipid raft metabolism are implicated in the pathogenesis of neurodegenerative disorders. They also describe techniques for the isolation of lipid rafts, the analysis of the lipid and protein components of lipid rafts, the imaging of lipid rafts in living cells, and the analysis of signal transduction in lipid rafts.Comprehensive and insightful, Membrane Microdomain Signaling: Lipid Rafts in Biology and Medicine offers researchers a multidisciplinary review of the latest basic, translational, and clinical research that promises to transform our understanding microdomain signaling mechanisms. 214 pp. Englisch. N° de réf. du vendeur 9781617375156
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Etat : New. Editor(s): Mattson, Mark P. Num Pages: 214 pages, biography. BIC Classification: PSF. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 13. Weight in Grams: 338. . 2010. 1st ed. Softcover of orig. ed. 2005. Paperback. . . . . N° de réf. du vendeur V9781617375156
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence . N° de réf. du vendeur 458521381
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Etat : New. pp. 226. N° de réf. du vendeur 263094385
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Taschenbuch. Etat : Neu. Membrane Microdomain Signaling | Lipid Rafts in Biology and Medicine | Mark P Mattson | Taschenbuch | x | Englisch | 2010 | Humana Press | EAN 9781617375156 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. N° de réf. du vendeur 107146532
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