A comprehensive collection of readily reproducible methods for studying receptors in silico, in vitro, and in vivo. These cutting-edge techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knockout mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan PCR. These book equips the researcher with techniques for exploring the unprecedented number of new receptor systems now emerging and the so-called "orphan" receptors whose activating ligand has not been identified.
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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A comprehensive collection of readily reproducible methods for studying receptors in silico, in vitro, and in vivo. These cutting-edge techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knockout mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan PCR. These book equips the researcher with techniques for exploring the unprecedented number of new receptor systems now emerging and the so-called 'orphan' receptors whose activating ligand has not been identified. Maintaining the high standards set by the successful first edition, Anthony P. Davenport and a panel of hands-on researchers from the pharmaceutical industry and academia take advantage of the latest developments to provide detailed practical methods for studying receptors in silico, in vitro, and in vivo. These readily reproducible techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knock-out mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan polymerase chain reaction (PCR). These ligand binding techniques are perfect for exploring the unprecedented number of new receptor systems now emerging and the so-called 'orphan' receptors whose activating ligand has not been identified. The protocols follow the successful Methods in Molecular Biology series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and state of the art, Receptor Binding Techniques, Second Edition offers academic and commercial researchers in the pharmaceutical and biotechnology industries a set of proven techniques for the successful characterization of receptors and the phenotyping of transgenic animals, including knock-outs. 240 pp. Englisch. N° de réf. du vendeur 9781617375569
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Etat : New. Editor(s): Davenport, Anthony P. Series: Methods in Molecular Biology. Num Pages: 240 pages, 71 black & white illustrations, biography. BIC Classification: MQP. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 14. Weight in Grams: 376. . 2010. 2nd ed. 2005. Paperback. . . . . N° de réf. du vendeur V9781617375569
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Etat : New. pp. 252 2nd Edition. N° de réf. du vendeur 263067665
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Etat : New. Print on Demand pp. 252 71 Illus. N° de réf. du vendeur 5861582
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Vendeur : Biblios, Frankfurt am main, HESSE, Allemagne
Etat : New. PRINT ON DEMAND pp. 252. N° de réf. du vendeur 183067675
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Taschenbuch. Etat : Neu. Receptor Binding Techniques | Anthony P Davenport | Taschenbuch | x | Englisch | 2010 | Humana Press | EAN 9781617375569 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. N° de réf. du vendeur 107146506
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Vendeur : moluna, Greven, Allemagne
Etat : New. A comprehensive collection of readily reproducible methods for studying receptors in silico, in vitro, and in vivo. These cutting-edge techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular method. N° de réf. du vendeur 458521422
Quantité disponible : Plus de 20 disponibles
Vendeur : Kennys Bookstore, Olney, MD, Etats-Unis
Etat : New. Editor(s): Davenport, Anthony P. Series: Methods in Molecular Biology. Num Pages: 240 pages, 71 black & white illustrations, biography. BIC Classification: MQP. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 14. Weight in Grams: 376. . 2010. 2nd ed. 2005. Paperback. . . . . Books ship from the US and Ireland. N° de réf. du vendeur V9781617375569
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