Reverse Transcriptase Inhibitors in HIV/AIDS Therapy - Couverture souple

Livre 15 sur 36: Infectious Disease
 
9781617376955: Reverse Transcriptase Inhibitors in HIV/AIDS Therapy

Synopsis

A magisterial survey of all aspects of the reverse transcriptase inhibitors (RTIs) used to treat HIV/AIDS, including drug discovery, pharmacology, development of drug resistance, toxicity, and prevention of mother-to-child transmission of HIV/AIDS. The authors synthesize our current understanding of the role of reverse transcriptase in the viral life cycle, describe the discovery and development of eight nucleoside and nucleotide analogs that represent milestones in treatment history, and thoroughly discuss the question of toxicity and resistance to this class of drugs. They also address three non-nucleoside RTIs and their pharmacokinetics and comparative clinical efficacy, new RTIs currently under development, and the impact of approved agents on treatment, in general, and on vertical transmission in the developing world.

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Autres éditions populaires du même titre

9781588296498: Reverse Transcriptase Inhibitors in HIV/ AIDS Therapy

Edition présentée

ISBN 10 :  1588296490 ISBN 13 :  9781588296498
Editeur : Humana Press Inc., 2006
Couverture rigide