Articles liés à Fluorouracil: Synthesis, Health Effects and Role in...

Fluorouracil: Synthesis, Health Effects and Role in Chemotherapy - Couverture rigide

 
9781620819708: Fluorouracil: Synthesis, Health Effects and Role in Chemotherapy
Couverture rigide
ISBN 10 : 1620819708 ISBN 13 : 9781620819708
Editeur : Nova Science Publishers Inc, 2012

Synopsis

The fluoropyrimidine 5-fluorouracil (5-FU), an antimetabolite drug, works by being incorporated in the RNA and DNA and by the inhibition of the nucleotide synthetic enzyme thymidylate synthase. It is widely used in the treatment of a range of cancers, including gastrointestinal, head and neck, and breast cancers. In this book, the authors present current research in the study of the synthesis, health effects and role in chemotherapy of fluorouracil. Topics discussed include the antiproliferative activities, cell-cycle regulation, apoptosis and cellular differentiation of acyclic 5-fluorouracil O, N-Acetals; 5-fluorouracil and its immunotoxicity and side effects; 5-fluorouracil application in the management of bleb failure; and cisplatin and 5-fluorouracil for the treatment of ovarian adenocarcinoma.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
Nova Science Publishers Inc
Date d'édition
2012
Langue
anglais
ISBN 10 
1620819708
ISBN 13 
9781620819708
Reliure
Relié
Numéro d'édition
1
Nombre de pages
148
Éditeur
Dário Longinho Alberto C, Britto Dobreiro Sebastiao E
Coordonnées du fabricant
non disponible
Personne responsable
non disponible