Mouse Models of Cancer - Couverture souple

Abate-Shen, Cory; Politi, Katerina; Chodosh, Lewis; Olive, Kenneth P

Couverture souple

ISBN 10 : 1621820033 ISBN 13 : 9781621820031

Editeur : Cold Spring Harbor Laboratory Press,U.S., 2013

Synopsis

"The laboratory mouse is an important model for studying cancer and its treatment. This book includes both background information and step-by-step protocols for generating mouse models that accurately recapitulate many features of human cancer. It covers genetic models, including transgenic germline models, gene knockouts and knockins, and conditional and inducible systems, as well as models derived using chemical carcinogens, RNA interference, tissue recombination, and other strategies. Techniques to characterize tumor development, progression, and metastasis in these mice using state-of-the-art imaging, histopathological, surgical, and other approaches are described. The uses of these models in preclinical and translational research are also discussed"--

Détails de l'édition

• Éditeur: Cold Spring Harbor Laboratory Press,U.S.
• Date d'édition: 2013
• Langue: anglais
• ISBN 10: 1621820033
• ISBN 13: 9781621820031
• Reliure: Broché
• Nombre de pages: 521
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible