The endoplasmic reticulum (ER) is a network of membranes that folds, modifies, and transports proteins in eukaryotic cells. It also manufactures lipids and interacts extensively with other organelles, playing essential roles in cell growth and homeostasis.
Written and edited by experts in the field, this new collection from Cold Spring Harbor Perspectives in Biology provides a comprehensive update on advances in our understanding of the structure and multiple functions of the ER. The contributors examine how proteins enter the ER, the biogenesis of membrane proteins, and the role of the ER in protein sorting and quality control. In addition, they discuss how lipids are synthesized and transported to and from the ER. The volume reviews the architecture of the ER and the ways in which it interacts with other organelles. The consequences for metabolic health and neurodegeneration are also considered. It is thus an essential reference for cell biologists, as well as physiologists and pathologists interested in understanding the role of the ER in disease.Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
Susan Ferro-Novick is Professor of Cellular and Molecular Medicine at the University of California, San Diego
Tom A. Rapoport is Professor of Cell Biology at Harvard Medical School
Randy Schekman is Professor of Cell Biology, Development and Physiology at University of California at Berkeley
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
Vendeur : Open Books, Chicago, IL, Etats-Unis
hardcover. Etat : New. Open Books is a nonprofit social venture that provides literacy experiences for thousands of readers each year through inspiring programs and creative capitalization of books. N° de réf. du vendeur mon0000760477
Quantité disponible : 1 disponible(s)