Type I Interferon in Autoimmune Diseases and Its Clinical Application - Couverture rigide

 
9781624173790: Type I Interferon in Autoimmune Diseases and Its Clinical Application
Couverture rigide
ISBN 10 : 1624173799 ISBN 13 : 9781624173790
Editeur : Nova Science Publishers Inc, 2013

Synopsis

Auto-immune diseases such as systemic lupus erythematosus (SLE), Sjögren's syndrome, psoriasis, scleroderma (SSc) and myositis are heterogeneous disorders that result from interactions between genetic and environmental factors. Type I interferons (IFNs), especially IFN-α/β, have multiple biological functions including anti-viral and anti-bacterial properties, immuno-modulation, anti-proliferation, and intensive studies over decades have also revealed important roles in auto-immunity and cancer. Sustained Type I IFN elevation has been implicated in immune responses against self-antigens and tissue damage, which has led to the hypothesis that type I IFN might play a critical role in the pathogenesis of some auto-immune and inflammatory diseases. This book provides an overview of many key topics surrounding type I IFNs, beginning with detailed discussion of the type I IFN signalling pathway, the interplay between components that regulate this pathway, its involvement in auto-immunity, and a detailed review of the roles of type I IFNs in a series of well characterised inflammatory and auto-immune diseases.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
Nova Science Publishers Inc
Date d'édition
2013
Langue
anglais
ISBN 10 
1624173799
ISBN 13 
9781624173790
Reliure
Relié
Numéro d'édition
1
Nombre de pages
349
Éditeur
Yao Yihong
Coordonnées du fabricant
Buchpark GmbH
https://www.buchpark.de

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