Ras Signaling: Methods and Protocols - Couverture rigide

Couverture rigide

ISBN 10 : 162703790X ISBN 13 : 9781627037907

Editeur : Humana Press Inc., 2014

Synopsis

Featuring experimental approaches that shed light on the complexity of Ras GTPase biological functions, Ras Signaling: Methods and Protocols contains general overviews and detailed applications of both well-established and recently developed research techniques, including biochemical, biophysical, molecular biology, genetic and behavioral approaches, advanced high resolution fluorescence and electron microscopy imaging and "omics" technologies. Through this, the detailed volume provides information on expression, post-translational modifications, subcellular localization and dynamics, regulatory mechanisms of upstream and downstream signaling pathways and ultimately, biological activities and functions of Ras GTPases in different model systems, including high and low eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.

Wide-ranging and authoritative, Ras Signaling: Methods and Protocols serves as an aid for investigators of different backgrounds and interests related to the multiple physiological and pathological functions of the large superfamily of Ras GTPases.

Détails de l'édition

• Éditeur: Humana Press Inc.
• Date d'édition: 2014
• Langue: anglais
• ISBN 10: 162703790X
• ISBN 13: 9781627037907
• Reliure: Relié
• Nombre de pages: 437
• Éditeur: Trabalzini Lorenza, Retta Saverio Francesco
• Coordonnées du fabricant: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Poststr. 9; Darmstadt; 64293; Allemagne