Salmonella Pathogenesis and Progression in the Development of Human and Veterinary Non-typhoidal Salmonella Vaccines Against Human Salmonellosis - Couverture souple

Lee, John Hwa

 
9781633218826: Salmonella Pathogenesis and Progression in the Development of Human and Veterinary Non-typhoidal Salmonella Vaccines Against Human Salmonellosis
Couverture souple
ISBN 10 : 1633218821 ISBN 13 : 9781633218826
Editeur : Nova Science Publishers Inc, 2014

Synopsis

The important foodborne zoonotic pathogen non-typhoidal Salmonella cause gastroenteritis, bacteremia and focal infection in humans. Salmonella evades the host's immune system through the coordinated expression of complex arrays of virulence associated-genes. The dynamics of host-pathogen Salmonella enterica interaction and infection might enhance the development of novel targeted preventative measures and drug regimens. However, widespread usage of antibiotics has led to the emergence of multiple antibiotic-resistant Salmonella. To avoid this problem, effective vaccines are developed to control non-typhoidal Salmonella zoonotic infections. An understanding of how Salmonella enterica spreads and survives in tissues has very important implications for targeting intracellular Salmonella with vaccine-induced immune responses. Application of advanced knowledge and scientific methods in the development of vaccines could diminish the non-typhoidal Salmonella disease burden globally. Currently, the oral live attenuated vaccines showed an efficient protection against non-typhoidal Salmonella zoonotic infection. However, inactivated or sub-unit vaccines are considered to be the safest over live vaccines. Ultimately, this review explores the molecular basis of non-typhoidal Salmonella pathogenesis. In addition to pathogenesis, recent advances in generation of Salmonella vaccines are also emphasised. This review also gives a deep insight into the future development of Salmonella vaccines with different innovations.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Éditeur
Nova Science Publishers Inc
Date d'édition
2014
Langue
anglais
ISBN 10 
1633218821
ISBN 13 
9781633218826
Reliure
Broché
Nombre de pages
60
Coordonnées du fabricant
non disponible
Personne responsable
non disponible