Endoplasmic Reticulum Stress: Regulation, Function and Role in Health and Disease - Couverture souple

 
9781634855648: Endoplasmic Reticulum Stress: Regulation, Function and Role in Health and Disease
Couverture souple
ISBN 10 : 1634855647 ISBN 13 : 9781634855648
Editeur : Nova Science Publishers Inc, 2016

Synopsis

This book provides current research on the regulation, function and role in health and disease of endoplasmic reticulum (ER) stress. The first chapter focuses on evidence that supports the role of endoplasmic reticulum stress, mitochondria-associated membranes (MAMs) microdomain and oxidative stress during obesity as a molecular pathway to type 2 diabetes mellitus (T2DM) development. Also, it addresses protein missfolding and mitochondria function as potential targets to improve metabolic derangements in obesity and T2DM. Chapter Two summarizes and discusses the current understanding of molecular mechanisms linking ER stress to beta cell fate. Chapter Three depicts the association between eIF2α kinase-linked pathways and diet-linked pathogenic responses (such as ones caused by microbes or nutritional abnormalities). Chapter Four reviews placental endoplasmic reticulum stress in the determination of pregnancy outcome. The last chapter discusses the role of ER stress in meditating the anticancer effects of tocotrienols.

Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.

Présentation de l'éditeur

This book provides current research on the regulation, function and role in health and disease of endoplasmic reticulum (ER) stress. The first chapter focuses on evidence that supports the role of endoplasmic reticulum stress, mitochondria-associated membranes (MAMs) microdomain and oxidative stress during obesity as a molecular pathway to type 2 diabetes mellitus (T2DM) development. Also, it addresses protein missfolding and mitochondria function as potential targets to improve metabolic derangements in obesity and T2DM. Chapter Two summarizes and discusses the current understanding of molecular mechanisms linking ER stress to beta cell fate. Chapter Three depicts the association between eIF2α kinase-linked pathways and diet-linked pathogenic responses (such as ones caused by microbes or nutritional abnormalities). Chapter Four reviews placental endoplasmic reticulum stress in the determination of pregnancy outcome. The last chapter discusses the role of ER stress in meditating the anticancer effects of tocotrienols.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Éditeur
Nova Science Publishers Inc
Date d'édition
2016
Langue
anglais
ISBN 10 
1634855647
ISBN 13 
9781634855648
Reliure
Broché
Nombre de pages
123
Éditeur
Wagner Cameron
Coordonnées du fabricant
non disponible
Personne responsable
non disponible