Genetic Analysis: Integrating Genes and Genomes - Couverture rigide

Couverture rigide

ISBN 10 : 1680957414 ISBN 13 : 9781680957419

Editeur : Delve Publishing, 2016

Synopsis

The new advances in the field of genetics have led to numerous medical breakthroughs in the past few years. Genetic Analysis: Integrating Genes and Genomes provides an insight on the advances made in human genetics in the last few years. The editor has comprehensively assembled recent developments on the use of modern genetic analytical techniques and tools for answering biological questions related to genomic screening, mutations, gene and environment interactions, comparative and molecular genomic approaches for detecting genetic components of diseases.

A better understanding of the genetic basis of disease can be achieved by studying genetic diversity across human populations. The interaction of gene and environment and their effects on human-specific developmental traits, genetic influences on methylation across the human life course, interplay of genes and lifestyle, genetic basis of disease in the context of migration, exposure to toxic metals like Lead, and calculation of genetic risk of diseases in unrelated individuals have been discussed. In addition, the synergistic effects of genes involved in cancer development, fructose-1,6-bisphosphatase deficiency, vitiligo, psoriasis, severe hypertriglyceridemia, and susceptibility to mycobacterial infection are explored in some chapters. Use of small interfering RNAs (siRNA), microRNAs and SINE sequences in screening systems have also been discussed to identify genes.

In one of the articles, the general framework of whole exome sequence data analysis is outlined. Finally, we also present an article on ChemProt, a publicly available compilation of chemical-protein-disease annotation resources that enables the study of a molecule from cellular to clinical levels.

A propos du livre

À propos de l'auteur

Dr Prerna Pandey, a biotechnologist with several years of wet lab research experience, worked as a senior research fellow at International Center for Genetic Engineering and Biotechnology, New Delhi. Her field of research in PhD included isolation and molecular characterization of Geminiviruses, genome sequencing and gene annotation, and gene silencing using the RNA interference technology. She has published papers in peer-reviewed journals in the field, and has a submitted a number of annotated Geminiviral genome sequences in the GenBank, including two novel ones. Prerna has also completed her editing and proof-reading courses from Society for the promotion of Editors and Proof-readers, UK and now works as a freelance scientific writer and editor.

Détails de l'édition

• Éditeur: Delve Publishing
• Date d'édition: 2016
• Langue: anglais
• ISBN 10: 1680957414
• ISBN 13: 9781680957419
• Reliure: Relié
• Nombre de pages: 261
• Éditeur: Pandey Prerna
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible