The New Microbiology: From Microbiomes to CRISPR - Couverture souple

Cossart, Pascale

Couverture souple

ISBN 10 : 1683670108 ISBN 13 : 9781683670100

Editeur : American Society for Microbiology, 2018

Synopsis

Microbiology has undergone radical changes over the past few decades, ushering in an exciting new era in science. In The New Microbiology, Pascale Cossart tells a splendid story about the revolution in microbiology, especially in bacteriology. This story has wide-ranging implications for human health and medicine, agriculture, environmental science, and our understanding of evolution. The revolution results from the powerful tools of molecular and cellular biology, genomics, and bioinformatics, which have yielded amazing discoveries, from entire genome sequences to video of bacteria invading host cells. This book is for both scientists and especially nonscientists who would like to learn more about the extraordinary world of bacteria.

Dr. Cossart's overview of the field of microbiology research, from infectious disease history to the ongoing scientific revolution resulting from CRISPR technologies, is presented in four parts.

• New concepts in microbiology introduces the world of bacteria and some recent discoveries about how they live, such as the role of regulatory RNAs including riboswitches, the CRISPR defense system, and resistance to antibiotics.
• Sociomicrobiology: the social lives of bacteria helps us see the new paradigm by which scientists view bacteria as highly social creatures that communicate in many ways, for example in the assemblies that reside in our intestine or in the environment.
• The biology of infections reviews some of history's worst epidemics and describes current and emerging infectious diseases, the organisms that cause them, and how they produce an infection.
• Bacteria as tools introduces us to molecules derived from microbes that scientists have harnessed in the service of research and medicine, including the CRISPR/Cas9 genome-editing technology.

The New Microbiology takes us on a journey through a remarkable revolution in science that is occurring here and now.

A propos du livre

Présentation de l'éditeur

Microbiology has undergone radical changes over the past few decades and ushered in an exciting new era in science. Microbes, specifically bacteria, are incredibly diverse: some are associated with disease and many others are essential for health. Bacteria are highly complex life forms able to communicate with each other and form mutually beneficial relationships with organisms they colonize. In plants, humans, and other animals, communities of microbes form biofilms and microbiota that use incredibly sophisticated strategies to influence their environment.

The study of bacterial immune systems has led to a revolution: the development of the CRISPR/Cas9 system, a precise tool for editing DNA whose usefulness we are just beginning to imagine. Bacteria in both health and disease are at the forefront of global challenges we face today. They evolve to resist the antibiotics used against them, but they can also be used to modify mosquitoes that serve as carriers of diseases like malaria. As we learn about the complex and vitally important intestinal microbiome, it unlocks secrets to good health and potential treatments for problems such as obesity

Biographie de l'auteur

Institut Pasteur, France.

Détails de l'édition

• Éditeur: American Society for Microbiology
• Date d'édition: 2018
• Langue: anglais
• ISBN 10: 1683670108
• ISBN 13: 9781683670100
• Reliure: Broché
• Nombre de pages: 200
• Coordonnées du fabricant: non disponible
• Personne responsable: non disponible